ENSMUSG00000019054


Mus musculus

Features
Gene ID: ENSMUSG00000019054
  
Biological name :Fis1
  
Synonyms : Fis1 / Mitochondrial fission 1 protein / Q9CQ92
  
Possible biological names infered from orthology : fission, mitochondrial 1 / Q9Y3D6
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 136953275
Gene end: 136966234
  
Corresponding Affymetrix probe sets: 10526508 (MoGene1.0st)   1416764_at (Mouse Genome 430 2.0 Array)   1443819_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019198
Ensembl peptide - ENSMUSP00000106723
Ensembl peptide - ENSMUSP00000106726
NCBI entrez gene - 66437     See in Manteia.
MGI - MGI:1913687
RefSeq - XM_006504489
RefSeq - NM_001163243
RefSeq - NM_025562
RefSeq Peptide - NP_001156715
RefSeq Peptide - NP_001334433
RefSeq Peptide - NP_079838
swissprot - D3YZ32
swissprot - G3X9U9
swissprot - Q9CQ92
Ensembl - ENSMUSG00000019054
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fis1ENSDARG00000114549Danio rerio
 FIS1ENSG00000214253Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR016543  Mitochondria fission 1 protein
 IPR028058  Fis1, N-terminal tetratricopeptide repeat
 IPR028061  Fis1, C-terminal tetratricopeptide repeat
 IPR033745  Mitochondria fission protein Fis1, cytosolic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000266 mitochondrial fission ISO
 biological_processGO:0000422 autophagy of mitochondrion IEA
 biological_processGO:0001836 release of cytochrome c from mitochondria IEA
 biological_processGO:0006626 protein targeting to mitochondrion IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0008053 mitochondrial fusion IEA
 biological_processGO:0010821 regulation of mitochondrion organization IEA
 biological_processGO:0016559 peroxisome fission IEA
 biological_processGO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration IEA
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source IEA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043653 mitochondrial fragmentation involved in apoptotic process IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051561 positive regulation of mitochondrial calcium ion concentration IEA
 biological_processGO:0070584 mitochondrion morphogenesis IEA
 biological_processGO:0090141 positive regulation of mitochondrial fission IEA
 biological_processGO:0090314 positive regulation of protein targeting to membrane IEA
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005777 peroxisome ISO
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0005779 integral component of peroxisomal membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031307 integral component of mitochondrial outer membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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