ENSMUSG00000019826


Mus musculus

Features
Gene ID: ENSMUSG00000019826
  
Biological name :Zbtb24
  
Synonyms : Q80X44 / Zbtb24 / zinc finger and BTB domain containing 24
  
Possible biological names infered from orthology : O43167
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B2
Gene start: 41450383
Gene end: 41465574
  
Corresponding Affymetrix probe sets: 10362758 (MoGene1.0st)   1438218_at (Mouse Genome 430 2.0 Array)   1442567_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000079592
Ensembl peptide - ENSMUSP00000148861
Ensembl peptide - ENSMUSP00000150197
NCBI entrez gene - 268294     See in Manteia.
MGI - MGI:3039618
RefSeq - XM_006512748
RefSeq - NM_001277229
RefSeq - NM_001277230
RefSeq - NM_153398
RefSeq Peptide - NP_001264159
RefSeq Peptide - NP_700447
RefSeq Peptide - NP_001264158
swissprot - Q80X44
Ensembl - ENSMUSG00000019826
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb24ENSDARG00000075533Danio rerio
 ZBTB24ENSGALG00000015231Gallus gallus
 O43167ENSG00000112365Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q60821 / Zbtb17 / zinc finger and BTB domain containing 17 / Q13105*ENSMUSG0000000621524
Q8K3J5 / Zfp131 / zinc finger protein 131 / P52739* / ZNF131*ENSMUSG0000009487018


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
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Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0003020 decreased circulating chloride level "reduced concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0010097 abnormal retinal blood vessel morphology "any structural anomaly of the blood vessels supplying the retina" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0011095 complete embryonic lethality between implantation and placentation "death of all organisms of a given genotype in a population between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith]
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Allelic Composition: Cyp26b1tm1Hh/Cyp26b1tm1Hh,Tg(Prox1-EGFP)KY221Gsat/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/NTac

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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