ENSMUSG00000019838


Mus musculus

Features
Gene ID: ENSMUSG00000019838
  
Biological name :Slc16a10
  
Synonyms : Q3U9N9 / Slc16a10 / solute carrier family 16 (monocarboxylic acid transporters), member 10
  
Possible biological names infered from orthology : Q8TF71 / solute carrier family 16 member 10
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B1
Gene start: 40033532
Gene end: 40142258
  
Corresponding Affymetrix probe sets: 10368720 (MoGene1.0st)   1434592_at (Mouse Genome 430 2.0 Array)   1436368_at (Mouse Genome 430 2.0 Array)   1440569_at (Mouse Genome 430 2.0 Array)   1453675_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000090227
Ensembl peptide - ENSMUSP00000150416
Ensembl peptide - ENSMUSP00000151126
NCBI entrez gene - 72472     See in Manteia.
MGI - MGI:1919722
RefSeq - XM_006512863
RefSeq - NM_001114332
RefSeq - NM_028247
RefSeq Peptide - NP_001107804
RefSeq Peptide - NP_082523
swissprot - Q3U9N9
swissprot - A0A1L1SVB8
Ensembl - ENSMUSG00000019838
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A1L1W9ENSDARG00000020984Danio rerio
 SLC16A10ENSGALG00000015040Gallus gallus
 Q8TF71ENSG00000112394Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O70324 / Slc16a2 / solute carrier family 16 (monocarboxylic acid transporters), member 2 / P36021* / solute carrier family 16 member 2*ENSMUSG0000003396550
Q7TM99 / Slc16a9 / solute carrier family 16 (monocarboxylic acid transporters), member 9 / Q7RTY1* / solute carrier family 16 member 9*ENSMUSG0000003776223
Q8K1C7 / Slc16a14 / solute carrier family 16 (monocarboxylic acid transporters), member 14 / Q7RTX9* / solute carrier family 16 member 14*ENSMUSG0000002622023
Q8R0M8 / Slc16a4 / solute carrier family 16 (monocarboxylic acid transporters), member 4 / O15374* / solute carrier family 16 member 4*ENSMUSG0000002789621


Protein motifs (from Interpro)
Interpro ID Name
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR030762  Monocarboxylate transporter 10
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015718 monocarboxylic acid transport IEA
 biological_processGO:0015801 aromatic amino acid transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070327 thyroid hormone transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 molecular_functionGO:0008028 monocarboxylic acid transmembrane transporter activity IBA
 molecular_functionGO:0015173 aromatic amino acid transmembrane transporter activity IEA
 molecular_functionGO:0015349 thyroid hormone transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Amino acid transport across the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001759 increased urine glucose level "a greater level of excretion of glucose in the urine compared to the normal state" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Ranbp9tm1Wyan/Ranbp9tm1Wyan,Tg(Stra8-icre)1Reb/0
Genetic Background: involves: C57BL/6J * FVB/NJ

 MP:0001762 polyuria "increased volume of urine produced and excreted" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Tg(SNCA)OVX37Rwm/0
Genetic Background: B6.Cg-Tg(SNCA)OVX37Rwm Sncatm1Rosl

 MP:0003311 aminoaciduria "excretion of amino acids in the urine, especially in excessive amounts" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:66560]
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Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Tg(SNCA)OVX37Rwm/0
Genetic Background: B6.Cg-Tg(SNCA)OVX37Rwm Sncatm1Rosl

 MP:0005311 abnormal circulating amino acid level "aberrant concentration in the blood of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:83263]
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Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Tg(SNCA)OVX37Rwm/0
Genetic Background: B6.Cg-Tg(SNCA)OVX37Rwm Sncatm1Rosl

 MP:0005332 abnormal amino acid level "aberrant concentration of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Tg(SNCA)OVX37Rwm/0
Genetic Background: B6.Cg-Tg(SNCA)OVX37Rwm Sncatm1Rosl

 MP:0009349 increased urine pH "increased urine alkalinity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Tg(SNCA)OVX37Rwm/0
Genetic Background: B6.Cg-Tg(SNCA)OVX37Rwm Sncatm1Rosl

 MP:0011468 abnormal urine amino acid level "any anomaly in the amount in the urine of a carboxylic acid containing one or more amino groups (-NH2) and a carboxyl (-COOH) group" [CHEBI:33709, MGI:csmith]
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Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Tg(SNCA)OVX37Rwm/0
Genetic Background: B6.Cg-Tg(SNCA)OVX37Rwm Sncatm1Rosl

 MP:0011470 increased urine creatinine level "an increased amount of creatinine in the urine compared to the normal state" [MGI:csmith]
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Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Tg(SNCA)OVX37Rwm/0
Genetic Background: B6.Cg-Tg(SNCA)OVX37Rwm Sncatm1Rosl

 MP:0011941 increased fluid intake "increase in the total amount of fluid taken in over time when compared to the normal state" [MGI:csmith]
Show

Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Tg(SNCA)OVX37Rwm/0
Genetic Background: B6.Cg-Tg(SNCA)OVX37Rwm Sncatm1Rosl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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