ENSMUSG00000019917


Mus musculus

Features
Gene ID: ENSMUSG00000019917
  
Biological name :Sept10
  
Synonyms : Sept10 / septin 10
  
Possible biological names infered from orthology : Q9P0V9
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B4
Gene start: 59141627
Gene end: 59221847
  
Corresponding Affymetrix probe sets: 10369252 (MoGene1.0st)   1437208_at (Mouse Genome 430 2.0 Array)   1438804_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000129023
Ensembl peptide - ENSMUSP00000151948
Ensembl peptide - ENSMUSP00000151293
NCBI entrez gene - 103080     See in Manteia.
MGI - MGI:1918110
RefSeq - XM_011243256
RefSeq - NM_001024910
RefSeq - NM_001024911
RefSeq - XM_011243255
RefSeq Peptide - NP_001020081
RefSeq Peptide - NP_001020082
swissprot - A0A1W2P866
swissprot - A0A1W2P6J7
swissprot - A0A0R4J233
Ensembl - ENSMUSG00000019917
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sept10ENSDARG00000099236Danio rerio
 ENSGALG00000016811Gallus gallus
 Q9P0V9ENSG00000186522Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sept8 / Q8CHH9 / Mus musculus septin 8 (Sept8), transcript variant 4, mRNA. / Q92599* / septin 8*ENSMUSG0000001839873
Q8C1B7 / Sept11 / septin 11 / Q9NVA2*ENSMUSG0000005801371
Sept6 / Q9R1T4 / Septin-6 / Q14141*ENSMUSG0000005037970
Q9DA97 / Sept14 / Septin-14 / Q6ZU15*ENSMUSG0000003421964


Protein motifs (from Interpro)
Interpro ID Name
 IPR016491  Septin
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030379  Septin-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Ralatm1a(EUCOMM)Wtsi/Ralatm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ralatm1a(EUCOMM)Wtsi/Wtsi

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Ralatm1a(EUCOMM)Wtsi/Ralatm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ralatm1a(EUCOMM)Wtsi/Wtsi

 MP:0003047 abnormal thoracic vertebrae morphology "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0003345 decreased number of ribs "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Ralatm1a(EUCOMM)Wtsi/Ralatm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ralatm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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