ENSMUSG00000019961


Mus musculus

Features
Gene ID: ENSMUSG00000019961
  
Biological name :Tmpo
  
Synonyms : Q61029 / Q61033 / thymopoietin / Tmpo
  
Possible biological names infered from orthology : P42166 / P42167
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C2
Gene start: 91147571
Gene end: 91181315
  
Corresponding Affymetrix probe sets: 10371888 (MoGene1.0st)   1421237_at (Mouse Genome 430 2.0 Array)   1426020_at (Mouse Genome 430 2.0 Array)   1426349_s_at (Mouse Genome 430 2.0 Array)   1428976_at (Mouse Genome 430 2.0 Array)   1452036_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000096956
Ensembl peptide - ENSMUSP00000072092
Ensembl peptide - ENSMUSP00000089864
Ensembl peptide - ENSMUSP00000020123
Ensembl peptide - ENSMUSP00000100930
NCBI entrez gene - 21917     See in Manteia.
MGI - MGI:106920
RefSeq - XM_006513590
RefSeq - NM_001080129
RefSeq - NM_001080130
RefSeq - NM_001080131
RefSeq - NM_001080132
RefSeq - NM_001283048
RefSeq - NM_011605
RefSeq Peptide - NP_001073598
RefSeq Peptide - NP_001073600
RefSeq Peptide - NP_001073601
RefSeq Peptide - NP_001269977
RefSeq Peptide - NP_035735
RefSeq Peptide - NP_001073599
swissprot - Q61029
swissprot - Q61033
swissprot - Q3TNH0
Ensembl - ENSMUSG00000019961
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmpoaENSDARG00000007315Danio rerio
 tmpobENSDARG00000022978Danio rerio
 TMPOENSGALG00000011504Gallus gallus
 TMPOENSG00000120802Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003887  LEM domain
 IPR011015  LEM/LEM-like domain superfamily
 IPR013146  LEM-like domain
 IPR021623  Lamina-associated polypeptide 2 alpha, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005635 nuclear envelope ISO
 cellular_componentGO:0005637 nuclear inner membrane IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
Depolymerisation of the Nuclear Lamina


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000572 abnormal autopod morphology "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Grin1tm1Rsp/Grin1tm1Rsp,Tg(Slc6a3-icre)9075Gsc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001219 thickened epidermis "increase in the width of the epidermal cell layer in the skin" [J:65146]
Show

Allelic Composition: Grin1tm1Rsp/Grin1tm1Rsp,Tg(Slc6a3-icre)9075Gsc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002608 increased hematocrit "greater than average percentage of a volume of a blood sample occupied by red blood cells" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Grin1tm1Rsp/Grin1tm1Rsp,Tg(Slc6a3-icre)9075Gsc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003077 abnormal cell cycle "failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266]
Show

Allelic Composition: Grin1tm1Rsp/Grin1tm1Rsp,Tg(Slc6a3-icre)9075Gsc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003135 increased erythrocyte precursors "greater numbers of progenitors of the erythrocyte lineage" [smb:Susan M. Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Grin1tm1Rsp/Grin1tm1Rsp,Tg(Slc6a3-icre)9075Gsc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004842 abnormal large intestine crypts of Lieberkuhn morphology "any structural anomaly in the tubular intestinal glands found in the mucosal membranes of the large intestine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Grin1tm1Rsp/Grin1tm1Rsp,Tg(Slc6a3-icre)9075Gsc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0008883 abnormal enterocyte proliferation "anomaly in the ability of the enterocyte cell population to undergo expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Grin1tm1Rsp/Grin1tm1Rsp,Tg(Slc6a3-icre)9075Gsc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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