ENSMUSG00000020173


Mus musculus

Features
Gene ID: ENSMUSG00000020173
  
Biological name :Cobl
  
Synonyms : Cobl / Protein cordon-bleu / Q5NBX1
  
Possible biological names infered from orthology : cordon-bleu WH2 repeat protein / O75128
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: A1
Gene start: 12236608
Gene end: 12464960
  
Corresponding Affymetrix probe sets: 10384423 (MoGene1.0st)   1434917_at (Mouse Genome 430 2.0 Array)   1442076_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000134372
Ensembl peptide - ENSMUSP00000045693
Ensembl peptide - ENSMUSP00000105277
Ensembl peptide - ENSMUSP00000105278
Ensembl peptide - ENSMUSP00000114779
Ensembl peptide - ENSMUSP00000119008
Ensembl peptide - ENSMUSP00000133368
Ensembl peptide - ENSMUSP00000133470
Ensembl peptide - ENSMUSP00000133669
NCBI entrez gene - 12808     See in Manteia.
MGI - MGI:105056
RefSeq - XM_011243655
RefSeq - XM_006514485
RefSeq - XM_006514481
RefSeq - XM_011243654
RefSeq - XM_011243653
RefSeq - XM_011243652
RefSeq - NM_001282993
RefSeq - NM_001282994
RefSeq - NM_172496
RefSeq - XM_011243656
RefSeq - XM_011243651
RefSeq Peptide - NP_001269923
RefSeq Peptide - NP_001269922
RefSeq Peptide - NP_766084
swissprot - Q5NBX1
swissprot - F6ZEZ1
swissprot - F6RR81
swissprot - G5E8P4
swissprot - G3UZ73
swissprot - G3UWY3
swissprot - G3UWP1
Ensembl - ENSMUSG00000020173
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 coblENSDARG00000091006Danio rerio
 COBLENSGALG00000013102Gallus gallus
 COBLENSG00000106078Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cobll1 / Q3UMF0 / Cordon-bleu protein-like 1 / Q53SF7* / cordon-bleu WH2 repeat protein like 1*ENSMUSG0000003490316


Protein motifs (from Interpro)
Interpro ID Name
 IPR003124  WH2 domain
 IPR019025  Cordon-bleu, ubiquitin-like domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000578 embryonic axis specification IEP
 biological_processGO:0001757 somite specification IEP
 biological_processGO:0001843 neural tube closure IGI
 biological_processGO:0001889 liver development IEP
 biological_processGO:0030041 actin filament polymerization IMP
 biological_processGO:0030903 notochord development IEP
 biological_processGO:0033504 floor plate development IEP
 biological_processGO:0048565 digestive tract development IEP
 biological_processGO:0048669 collateral sprouting in absence of injury IMP
 biological_processGO:0051639 actin filament network formation IDA
 biological_processGO:0051764 actin crosslink formation NAS
 biological_processGO:1900006 positive regulation of dendrite development IDA
 biological_processGO:1900029 positive regulation of ruffle assembly IDA
 cellular_componentGO:0001726 ruffle IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005884 actin filament IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0044294 dendritic growth cone IDA
 cellular_componentGO:0044295 axonal growth cone IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:1990357 terminal web IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0003785 actin monomer binding IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Terctm1Rdp/Terctm1Rdp,Terf1tm1Tdl/Terf1tm1Tdl
Genetic Background: involves: 129S2/SvPas

Allelic Composition: CoblC101/CoblC101,Vangl2Lp/Vangl2+
Genetic Background: involves: 129S2/SvPas * LPT/LeJ

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc12a2tm2Bhk/Slc12a2tm2Bhk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr