ENSMUSG00000020196


Mus musculus

Features
Gene ID: ENSMUSG00000020196
  
Biological name :Cabin1
  
Synonyms : Cabin1 / calcineurin binding protein 1
  
Possible biological names infered from orthology : Q9Y6J0
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 75646112
Gene end: 75764341
  
Corresponding Affymetrix probe sets: 10369948 (MoGene1.0st)   1433686_at (Mouse Genome 430 2.0 Array)   1437794_at (Mouse Genome 430 2.0 Array)   1440596_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001712
Ensembl peptide - ENSMUSP00000152043
Ensembl peptide - ENSMUSP00000151933
Ensembl peptide - ENSMUSP00000151879
Ensembl peptide - ENSMUSP00000151485
Ensembl peptide - ENSMUSP00000151436
NCBI entrez gene - 104248     See in Manteia.
MGI - MGI:1298375
RefSeq - XM_006513021
RefSeq - NM_172549
RefSeq - XM_006513019
RefSeq - XM_006513020
RefSeq Peptide - NP_766137
swissprot - A0A1W2P8A1
swissprot - A0A1W2P8C4
swissprot - G3X8Q1
swissprot - A0A1W2P819
swissprot - A0A1W2P755
swissprot - A0A1W2P6X4
Ensembl - ENSMUSG00000020196
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cabin1ENSDARG00000079326Danio rerio
 si:ch73-313l22.2ENSDARG00000094868Danio rerio
 CABIN1ENSGALG00000006363Gallus gallus
 CABIN1ENSG00000099991Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR015134  Calcineurin-binding protein cabin-1, MEF2-binding domain
 IPR019734  Tetratricopeptide repeat
 IPR033053  Histone transcription regulator 3/CABIN1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006336 DNA replication-independent nucleosome assembly ISO
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016235 aggresome ISO
 molecular_functionGO:0004864 protein phosphatase inhibitor activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031491 nucleosome binding IBA


Pathways (from Reactome)
Pathway description
Formation of Senescence-Associated Heterochromatin Foci (SAHF)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001800 abnormal humoral immune response "abnormal immune function mediated by antibodies" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Gsk3btm1Jrw/Gsk3b+,Runx2tm1Kish/Runx2+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0002497 increased IgE "greater than normal immunoglobulin class E level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gsk3btm1Jrw/Gsk3b+,Runx2tm1Kish/Runx2+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0003009 abnormal cytokine secretion "impairment or increase of the cellular release of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells " [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, smb:Susan M. Bello , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gsk3btm1Jrw/Gsk3b+,Runx2tm1Kish/Runx2+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0008499 increased IgG1 level "greater than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gsk3btm1Jrw/Gsk3b+,Runx2tm1Kish/Runx2+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0008501 increased IgG2b level "greater than normal immunoglobulin class G2b level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gsk3btm1Jrw/Gsk3b+,Runx2tm1Kish/Runx2+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Gsk3btm1Jrw/Gsk3b+,Runx2tm1Kish/Runx2+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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