ENSMUSG00000020405


Mus musculus

Features
Gene ID: ENSMUSG00000020405
  
Biological name :Fabp6
  
Synonyms : Fabp6 / Gastrotropin / P51162
  
Possible biological names infered from orthology : fatty acid binding protein 6 / P51161
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B1.1
Gene start: 43596049
Gene end: 43601540
  
Corresponding Affymetrix probe sets: 10385337 (MoGene1.0st)   1450682_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020672
NCBI entrez gene - 16204     See in Manteia.
MGI - MGI:96565
RefSeq - NM_008375
RefSeq Peptide - NP_032401
swissprot - P51162
Ensembl - ENSMUSG00000020405
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fabp6ENSDARG00000044566Danio rerio
 FABP6ENSGALG00000001445Gallus gallus
 FABP6ENSG00000170231Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fabp1 / P12710 / Fatty acid-binding protein, liver / P07148* / fatty acid binding protein 1*ENSMUSG0000005442241


Protein motifs (from Interpro)
Interpro ID Name
 IPR000463  Cytosolic fatty-acid binding
 IPR012674  Calycin
 IPR031257  Gastrotropin
 IPR031259  Intracellular lipid binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0008206 bile acid metabolic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0032052 bile acid binding IEA


Pathways (from Reactome)
Pathway description
Recycling of bile acids and salts
Triglyceride catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Ccbe1tm1Mlkn/Ccbe1tm1Mlkn
Genetic Background: either: B6.129-Ccbe1tm1Mlkn or (involves: 129 * C57BL/6)

 MP:0003402 decreased liver weight "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ccbe1tm1Mlkn/Ccbe1tm1Mlkn
Genetic Background: either: B6.129-Ccbe1tm1Mlkn or (involves: 129 * C57BL/6)

 MP:0004789 increased bile salt level "increased concentration of the steroid salts derived from cholesterol in the liver, produced as bile acids and secreted in the biliary sytem as bile salts; these play an important role in the digestion and absorption of fats" [MESH:D04.808.105, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ccbe1tm1Mlkn/Ccbe1tm1Mlkn
Genetic Background: either: B6.129-Ccbe1tm1Mlkn or (involves: 129 * C57BL/6)

 MP:0005179 decreased total circulating cholesterol level "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ccbe1tm1Mlkn/Ccbe1tm1Mlkn
Genetic Background: either: B6.129-Ccbe1tm1Mlkn or (involves: 129 * C57BL/6)

 MP:0005365 abnormal bile salt homeostasis "anomalous regulation of the steroid salts derived from cholesterol in the liver and which play an important role in the digestion and absorption of fats" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:86154]
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Allelic Composition: Ccbe1tm1Mlkn/Ccbe1tm1Mlkn
Genetic Background: either: B6.129-Ccbe1tm1Mlkn or (involves: 129 * C57BL/6)

 MP:0010026 decreased liver cholesterol level "less than normal amount in the liver of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ccbe1tm1Mlkn/Ccbe1tm1Mlkn
Genetic Background: either: B6.129-Ccbe1tm1Mlkn or (involves: 129 * C57BL/6)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000029368 Alb / P07724 / Serum albumin / P02768* / albumin*  / reaction






 

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