ENSMUSG00000020739


Mus musculus

Features
Gene ID: ENSMUSG00000020739
  
Biological name :Nup85
  
Synonyms : Nuclear pore complex protein Nup85 / Nup85 / Q8R480
  
Possible biological names infered from orthology : nucleoporin 85 / Q9BW27
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 115564434
Gene end: 115583985
  
Corresponding Affymetrix probe sets: 10382542 (MoGene1.0st)   1416073_a_at (Mouse Genome 430 2.0 Array)   1437520_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021085
Ensembl peptide - ENSMUSP00000116069
Ensembl peptide - ENSMUSP00000117333
NCBI entrez gene - 445007     See in Manteia.
MGI - MGI:3046173
RefSeq - XM_006533671
RefSeq - NM_001002929
RefSeq - XM_006533670
RefSeq Peptide - NP_001002929
swissprot - Q8R480
swissprot - Z4YLV0
swissprot - Z4YM95
Ensembl - ENSMUSG00000020739
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nucleoporin 85ENSDARG00000112002Danio rerio
 nup85ENSDARG00000098679Danio rerio
 NUP85ENSGALG00000007974Gallus gallus
 NUP85ENSG00000125450Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011502  Nucleoporin Nup85-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006406 mRNA export from nucleus IBA
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0006935 chemotaxis IDA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway ISA
 biological_processGO:0030032 lamellipodium assembly IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 biological_processGO:0048246 macrophage chemotaxis IDA
 biological_processGO:0051028 mRNA transport IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore ISO
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane ISA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031080 nuclear pore outer ring IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0017056 structural constituent of nuclear pore IBA
 molecular_functionGO:0031727 CCR2 chemokine receptor binding ISA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of Mature mRNA derived from an Intron-Containing Transcript
Regulation of Glucokinase by Glucokinase Regulatory Protein
snRNP Assembly
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Nampttm1.1(KOMP)Vlcg/Nampttm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nampttm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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