ENSMUSG00000020744


Mus musculus

Features
Gene ID: ENSMUSG00000020744
  
Biological name :Slc25a19
  
Synonyms : Mitochondrial thiamine pyrophosphate carrier / Q9DAM5 / Slc25a19
  
Possible biological names infered from orthology : Q9HC21 / solute carrier family 25 member 19
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E2
Gene start: 115614178
Gene end: 115628295
  
Corresponding Affymetrix probe sets: 10392983 (MoGene1.0st)   1424316_at (Mouse Genome 430 2.0 Array)   1424317_at (Mouse Genome 430 2.0 Array)   1437459_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114566
Ensembl peptide - ENSMUSP00000102112
Ensembl peptide - ENSMUSP00000115742
Ensembl peptide - ENSMUSP00000137534
Ensembl peptide - ENSMUSP00000120390
Ensembl peptide - ENSMUSP00000116005
Ensembl peptide - ENSMUSP00000021089
NCBI entrez gene - 67283     See in Manteia.
MGI - MGI:1914533
RefSeq - XM_017314714
RefSeq - NM_001252384
RefSeq - NM_001252394
RefSeq - NM_001252395
RefSeq - NM_001252396
RefSeq - NM_026071
RefSeq - XM_006533979
RefSeq - XM_011249183
RefSeq Peptide - NP_001239313
RefSeq Peptide - NP_001239323
RefSeq Peptide - NP_001239324
RefSeq Peptide - NP_001239325
RefSeq Peptide - NP_080347
swissprot - A2A9V3
swissprot - A2A9V5
swissprot - A2A9V2
swissprot - A2A9V7
swissprot - Q9DAM5
swissprot - A2A9V4
Ensembl - ENSMUSG00000020744
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc25a19ENSDARG00000100385Danio rerio
 SLC25A19ENSGALG00000008011Gallus gallus
 Q9HC21ENSG00000125454Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002067  Mitochondrial carrier protein
 IPR018108  Mitochondrial substrate/solute carrier
 IPR023395  Mitochondrial carrier domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006839 mitochondrial transport IBA
 biological_processGO:0030974 thiamine pyrophosphate transmembrane transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071934 thiamine transmembrane transport IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031305 integral component of mitochondrial inner membrane IBA
 molecular_functionGO:0015234 thiamine transmembrane transporter activity IBA


Pathways (from Reactome)
Pathway description
Vitamin B1 (thiamin) metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000433 microcephaly "an abnormally small head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0000929 open neural tube "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0000930 wavy neural tube "undulations in the embryonic neural tube" [J:37888]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0001722 pale yolk sac "bloodless yolk sac" [J:62571]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0002893 ketoaciduria "excretion of urine having an elevated concentration of keto acids" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0006036 abnormal mitochondrial physiology 
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0012172 abnormal amniotic fluid composition "any alteration in the expected chemical makeup of the watery liquid within the amnion that surrounds and cushions a growing fetus; normally, early in gestation, amniotic fluid is similar to maternal plasma, mainly water with electrolytes, and later in gestation, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid" [MGI:anna]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0012677 absent brain ventricles "absence of one or more of the four communicating cavities within the brain that are continuous with the central canal of the spinal cord" [MGI:anna]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0013241 embryo tissue necrosis "morphological changes resulting from pathological death of some or all embryo tissue; usually due to irreversible damage" [MGI:csmith]
Show

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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