ENSMUSG00000020766


Mus musculus

Features
Gene ID: ENSMUSG00000020766
  
Biological name :Galk1
  
Synonyms : Galactokinase / Galk1 / Q9R0N0
  
Possible biological names infered from orthology : galactokinase 1 / P51570
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E2
Gene start: 116008457
Gene end: 116012719
  
Corresponding Affymetrix probe sets: 10393047 (MoGene1.0st)   1417177_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021114
NCBI entrez gene - 14635     See in Manteia.
MGI - MGI:95730
RefSeq - NM_016905
RefSeq Peptide - NP_058601
swissprot - Q9R0N0
Ensembl - ENSMUSG00000020766
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 galk1ENSDARG00000028088Danio rerio
 GALK1ENSGALG00000002311Gallus gallus
 GALK1ENSG00000108479Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Galk2 / Q68FH4 / N-acetylgalactosamine kinase / Q01415* / galactokinase 2*ENSMUSG0000002720732


Protein motifs (from Interpro)
Interpro ID Name
 IPR000705  Galactokinase
 IPR006203  GHMP kinase, ATP-binding, conserved site
 IPR006204  GHMP kinase N-terminal domain
 IPR006206  Mevalonate/galactokinase
 IPR013750  GHMP kinase, C-terminal domain
 IPR014721  Ribosomal protein S5 domain 2-type fold, subgroup
 IPR019539  Galactokinase galactose-binding domain
 IPR019741  Galactokinase, conserved site
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR036554  GHMP kinase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006012 galactose metabolic process ISO
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0019402 galactitol metabolic process IMP
 biological_processGO:0033499 galactose catabolic process via UDP-galactose IC
 biological_processGO:0046835 carbohydrate phosphorylation IEA
 biological_processGO:0061623 glycolytic process from galactose IMP
 cellular_componentGO:0005737 cytoplasm ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004335 galactokinase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0005534 galactose binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016773 phosphotransferase activity, alcohol group as acceptor IEA


Pathways (from Reactome)
Pathway description
Galactose catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
Show

Allelic Composition: Galk1tm1Stb/Galk1tm1Stb,Tg(Cryaa-AKR1B1)222Smch/0
Genetic Background: involves: 129S6/SvEvTac * C57BL * CBA

Allelic Composition: Galk1tm1Stb/Galk1tm1Stb,Tg(Cryaa-AKR1B1)648Smch/0
Genetic Background: involves: 129S6/SvEvTac * C57BL * CBA

 MP:0001764 abnormal homeostasis "anomaly in the state of equilibrium in the body with respect to various functions and to chemical composition of the fluids and tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gusbmps/Gusbmps
Genetic Background: B6.C-H2-Kbm1/ByBir-Gusbmps/J

Allelic Composition: Galk1tm1Stb/Galk1tm1Stb,Tg(Cryaa-AKR1B1)222Smch/0
Genetic Background: involves: 129S6/SvEvTac * C57BL * CBA

Allelic Composition: Galk1tm1Stb/Galk1tm1Stb,Tg(Cryaa-AKR1B1)648Smch/0
Genetic Background: involves: 129S6/SvEvTac * C57BL * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr