ENSMUSG00000027207


Mus musculus

Features
Gene ID: ENSMUSG00000027207
  
Biological name :Galk2
  
Synonyms : Galk2 / N-acetylgalactosamine kinase / Q68FH4
  
Possible biological names infered from orthology : galactokinase 2 / Q01415
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: F1
Gene start: 125859109
Gene end: 125984299
  
Corresponding Affymetrix probe sets: 10475630 (MoGene1.0st)   1455798_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120728
Ensembl peptide - ENSMUSP00000092186
Ensembl peptide - ENSMUSP00000121752
Ensembl peptide - ENSMUSP00000118930
Ensembl peptide - ENSMUSP00000119902
Ensembl peptide - ENSMUSP00000028636
NCBI entrez gene - 69976     See in Manteia.
MGI - MGI:1917226
RefSeq - XM_011239772
RefSeq - XM_006500153
RefSeq - XM_011239770
RefSeq - XM_006500154
RefSeq - NM_001291002
RefSeq - NM_175154
RefSeq Peptide - NP_780363
RefSeq Peptide - NP_001277931
swissprot - Q3U3H5
swissprot - Q68FH4
swissprot - Q8BUU7
swissprot - D6RJ57
swissprot - B7ZCT3
swissprot - B7ZCT4
swissprot - B7ZCT5
Ensembl - ENSMUSG00000027207
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 galk2ENSDARG00000004059Danio rerio
 GALK2ENSGALG00000036201Gallus gallus
 GALK2ENSG00000156958Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Galk1 / Q9R0N0 / Galactokinase / P51570* / galactokinase 1*ENSMUSG0000002076627


Protein motifs (from Interpro)
Interpro ID Name
 IPR000705  Galactokinase
 IPR006203  GHMP kinase, ATP-binding, conserved site
 IPR006204  GHMP kinase N-terminal domain
 IPR006206  Mevalonate/galactokinase
 IPR013750  GHMP kinase, C-terminal domain
 IPR014721  Ribosomal protein S5 domain 2-type fold, subgroup
 IPR019539  Galactokinase galactose-binding domain
 IPR019741  Galactokinase, conserved site
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR036554  GHMP kinase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006012 galactose metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046835 carbohydrate phosphorylation IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004335 galactokinase activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005534 galactose binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016773 phosphotransferase activity, alcohol group as acceptor IEA
 molecular_functionGO:0033858 N-acetylgalactosamine kinase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Folh1tm1b(KOMP)Wtsi/Folh1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Folh1tm1b(KOMP)Wtsi/J

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Folh1tm1b(KOMP)Wtsi/Folh1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Folh1tm1b(KOMP)Wtsi/J

 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Folh1tm1b(KOMP)Wtsi/Folh1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Folh1tm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr