| MP:0000410 | waved hair | "hair or fur having undulations or a sinusoidal shape" [J:47620] |
Show
Allelic Composition: Rhbdf2cub/Rhbdf2cub,AregMcub/Areg+
Genetic Background: involves: C57BL/6J * STOCK a us/J * V/LeJ
|
| MP:0000414 | alopecia | "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796] |
Show
Allelic Composition: Cdontm2Rsk/Cdontm2Rsk
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0000609 | abnormal liver physiology | "aberrant function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Ulk2tm1Thsn/Ulk2tm1Thsn
Genetic Background: B6.129-Ulk2tm1Thsn
|
| MP:0000652 | enlarged sebaceous gland | "increased size of the sebum secreting glands of the hair shaft" [J:30249] |
Show
Allelic Composition: Cdontm2Rsk/Cdontm2Rsk
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0001219 | thickened epidermis | "increase in the width of the epidermal cell layer in the skin" [J:65146] |
Show
Allelic Composition: Cdontm2Rsk/Cdontm2Rsk
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0001243 | abnormal dermal layer morphology | "malformed or atypical condition of the dermal layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:56777] |
Show
Allelic Composition: Cdontm2Rsk/Cdontm2Rsk
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0001274 | curly vibrissae | "whiskers twisted into coils or spirals" [J:47620] |
Show
Allelic Composition: Cdontm2Rsk/Cdontm2Rsk
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0001302 | eyelids open at birth | "widely open eyes instead of closed at perinatal stage" [J:51966] |
Show
Allelic Composition: Rhbdf2tm1Mak/Rhbdf2tm1Mak
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0001790 | abnormal immune system physiology | "deviation from the normal function of the immune system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Gde1tm1Crv/Gde1tm1Crv,Napepldtm1Crv/Napepldtm1Crv
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Rhbdf2M3Btlr/Rhbdf2M3Btlr
Genetic Background: C57BL/6J-Rhbdf2M3Btlr
Allelic Composition: Rhbdf2M3Btlr/Rhbdf2+
Genetic Background: C57BL/6J-Rhbdf2M3Btlr
|
| MP:0002081 | perinatal lethality | "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Rhbdf2tm1Mak/Rhbdf2tm1Mak
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0002412 | increased susceptibility to bacterial infection | "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Ulk2tm1Thsn/Ulk2tm1Thsn
Genetic Background: B6.129-Ulk2tm1Thsn
|
| MP:0002442 | abnormal leukocyte physiology | "abnormal function of any of the white blood cells (basophils, eosinophils, neutrophils, lymphocytes, or monocytes) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Notch2tm1.1Ecan/Notch2+
Genetic Background: involves: 129 * 129S1/Sv * C57BL/6J
|
| MP:0002459 | abnormal B cell physiology | "abnormal function of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Ulk2tm1Thsn/Ulk2tm1Thsn
Genetic Background: B6.129-Ulk2tm1Thsn
|
| MP:0002723 | abnormal immune serum protein physiology | "abnormal concentration or function of circulating immune proteins" [cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ulk2tm1Thsn/Ulk2tm1Thsn
Genetic Background: B6.129-Ulk2tm1Thsn
|
| MP:0003408 | increased width of hypertrophic chondrocyte zone | "increased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Rhbdf2tm1Mak/Rhbdf2tm1Mak
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0003691 | abnormal microglial cell function | "anomalous activity of the small neuroglial cells, possibly of mesodermal origin, which may become phagocytic, in areas of neural damage or inflammation" [hdene:Howard Dene , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Notch2tm1.1Ecan/Notch2+
Genetic Background: involves: 129 * 129S1/Sv * C57BL/6J
|
| MP:0003809 | abnormal hair shaft morphology | "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cdontm2Rsk/Cdontm2Rsk
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0008554 | decreased circulating tumor necrosis factor level | "reduction in the amount in the blood of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MESH:D12.644.276.374.500.800] |
Show
Allelic Composition: Ulk2tm1Thsn/Ulk2tm1Thsn
Genetic Background: B6.129-Ulk2tm1Thsn
Allelic Composition: Rhbdf2tm1.1Mfm/Rhbdf2tm1.1Mfm
Genetic Background: B6.129S-Rhbdf2tm1.1Mfm
|
| MP:0008561 | decreased tumor necrosis factor secretion | "reduction in the production or release of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MESH:D12.644.276.374.500.800] |
Show
Allelic Composition: Ulk2tm1Thsn/Ulk2tm1Thsn
Genetic Background: B6.129-Ulk2tm1Thsn
Allelic Composition: Rhbdf2tm1.1Mfm/Rhbdf2tm1.1Mfm
Genetic Background: B6.129S-Rhbdf2tm1.1Mfm
Allelic Composition: Rhbdf2m1Btlr/Rhbdf2m1Btlr
Genetic Background: C57BL/6J-Rhbdf2m1Btlr
Allelic Composition: Rhbdf2tm1a(KOMP)Wtsi/Rhbdf2tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N
Allelic Composition: Rhbdf2m1Btlr/Rhbdf2tm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N
Allelic Composition: Rhbdf2tm1Mak/Rhbdf2tm1Mak
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0009264 | failure of eyelid fusion | "the upper and lower thin folds of skin and muscle that cover the exposed portion of the eye do not fuse together during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Rhbdf2tm1Mak/Rhbdf2tm1Mak
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0009273 | abnormal hair shaft melanin granule shape | "the form of pigment polymers in the hair shaft differs compared to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Cdontm2Rsk/Cdontm2Rsk
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0009786 | decreased susceptibility to infection induced morbidity/mortality | "reduced likelihood that an organism will display the expected moribund state caused by a pathogenic invasion or from components of or toxins produced by pathogens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ulk2tm1Thsn/Ulk2tm1Thsn
Genetic Background: B6.129-Ulk2tm1Thsn
|
| MP:0009788 | increased susceptibility to bacterial infection induced morbidity/mortality | "increased likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ulk2tm1Thsn/Ulk2tm1Thsn
Genetic Background: B6.129-Ulk2tm1Thsn
|
| MP:0010591 | enlarged aortic valve | "an increase in the total area occupied by the aortic valve" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Rhbdf2tm1Mak/Rhbdf2tm1Mak
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0010593 | thick aortic valve cusps | "an increase in the ratio of the aortic valve cusp thickness to the aortic wall thickness" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Rhbdf2tm1Mak/Rhbdf2tm1Mak
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0010600 | enlarged pulmonary valve | "an increase in the total area occupied by the pulmonary valve" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Rhbdf2tm1Mak/Rhbdf2tm1Mak
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0010605 | thick pulmonary valve cusps | "an increase in the ratio of the pulmonary valve cusp thickness to the pulmonary artery wall thickness" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Rhbdf2tm1Mak/Rhbdf2tm1Mak
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0010626 | thick tricuspid valve cusps | |
Show
Allelic Composition: Rhbdf2tm1Mak/Rhbdf2tm1Mak
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0010627 | enlarged tricuspid valve | "an increase in the total area occupied by the tricuspid valve" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Rhbdf2tm1Mak/Rhbdf2tm1Mak
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0010685 | abnormal hair follicle inner root sheath morphology | "any structural anomaly of the multilayered tube composed of terminally differentiated hair follicle keratinocytes that is surrounded by the outer root sheath; the layers of the inner root sheath include the companion layer, Henle s layer, Huxley s layer and the inner root sheath cuticle" [PMID:19211055] |
Show
Allelic Composition: Cdontm2Rsk/Cdontm2Rsk
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
Show
Allelic Composition: Rhbdf1tm1.1Mfm/Rhbdf1tm1.1Mfm
Genetic Background: B6.129S-Rhbdf1tm1.1Mfm
Allelic Composition: Rhbdf1tm1.1Mfm/Rhbdf1tm1.1Mfm,Rhbdf2tm1.1Mfm/Rhbdf2tm1.1Mfm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6J
|
| MP:0020386 | adipose tissue inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in adipose tissue" [MGI:anna, PMID:24662293, PMID:24695736, PMID:26629401] |
Show
Allelic Composition: Cdontm2Rsk/Cdontm2Rsk
Genetic Background: involves: 129/Sv * C57BL/6
|
