MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1tm1a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi
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MP:0000433 | microcephaly | "an abnormally small head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Slc6a3tm1b(KOMP)Wtsi/Slc6a3+ Genetic Background: C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J
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MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Slc6a3tm1b(KOMP)Wtsi/Slc6a3+ Genetic Background: C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J
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MP:0000443 | abnormal snout morphology | "anomalous structure or development of the anterior facial part of the muzzle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Slc6a3tm1b(KOMP)Wtsi/Slc6a3+ Genetic Background: C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J
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MP:0000455 | abnormal maxilla morphology | "malformation of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Slc6a3tm1b(KOMP)Wtsi/Slc6a3+ Genetic Background: C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J
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MP:0000556 | abnormal hindlimb morphology | "malformation of the entire posterior extremities" [MGI:tc] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0000564 | syndactyly | "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
Allelic Composition: Smoc1Tn(sb-lacZ,GFP)IR3.1Jtak/Smoc1Tn(sb-lacZ,GFP)IR3.1Jtak Genetic Background: involves: C3H * C57BL/6 * DBA/2 * ICR
Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1tm1a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi
Allelic Composition: Smoc1tm1b(EUCOMM)Wtsi/Smoc1tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H
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MP:0000565 | oligodactyly | "congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Slc6a3tm1b(KOMP)Wtsi/Slc6a3+ Genetic Background: C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J
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MP:0000566 | synostosis | "osseous union of two bones that are not normally connected" [J:13049] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0000571 | interdigital webbing | "fold of skin, or web, between the toes that is not normally present" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0000572 | abnormal autopod morphology | "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0000576 | clubbed feet | "congenital deformation of the feet; foot is plantarflexed, inverted and adducted" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
Allelic Composition: Smoc1Tn(sb-lacZ,GFP)IR3.1Jtak/Smoc1Tn(sb-lacZ,GFP)IR3.1Jtak Genetic Background: involves: C3H * C57BL/6 * DBA/2 * ICR
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1+ Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi/H
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1tm1a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi
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MP:0001297 | microphthalmia | "reduced average size of the eyes" [J:18048] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0001325 | abnormal retina morphology | "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
Allelic Composition: Smoc1tm1b(EUCOMM)Wtsi/Smoc1tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H
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MP:0001326 | retinal degeneration | "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0001333 | absent optic nerve | "absence of the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
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Allelic Composition: Slc6a3tm1b(KOMP)Wtsi/Slc6a3+ Genetic Background: C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J
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MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
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Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1tm1a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0002075 | abnormal coat color | "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Slc38a10tm2a(EUCOMM)Wtsi/Slc38a10tm2a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Slc38a10tm2a(EUCOMM)Wtsi/H
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MP:0002110 | abnormal digit morphology | "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Slc6a3tm1b(KOMP)Wtsi/Slc6a3+ Genetic Background: C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J
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MP:0002546 | mydriasis | "dilation of one or both pupils" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Slc6a3tm1b(KOMP)Wtsi/Slc6a3+ Genetic Background: C57BL/6N-Slc6a3tm1b(KOMP)Wtsi/J
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MP:0002765 | short fibula | "reduced length of the lateral and smaller of bone of the lower leg" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:12736] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0002792 | abnormal retinal vascularization | "malformation or disorganization of the blood vessels supplying the retina" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Smoc1tm1b(EUCOMM)Wtsi/Smoc1tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H
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MP:0002875 | decreased erythrocyte count | "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Scribtm1b(NCOM)Mfgc/Scribtm1b(NCOM)Mfgc Genetic Background: C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp
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MP:0002932 | abnormal joint | "defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0003345 | decreased number of ribs | "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Smoc1tm1b(EUCOMM)Wtsi/Smoc1tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H
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MP:0003757 | high palate | "greater distance upward to the roof of the oral cavity than usual" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0004358 | bowed tibia | "increased curvature of the medial and larger of the two bones of the lower leg" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0004509 | abnormal pelvic girdle bone morphology | "any structural anomaly of the bones of the pelvis by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Smoc1tm1b(EUCOMM)Wtsi/Smoc1tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H
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MP:0004642 | fused metatarsal bones | "improper union of the five bones of the hindpaws/feet that articulate proximally with the cuneiform and cuboid bones of the tarsus and distally with the phalanges" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0004924 | abnormal behavior | "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Scribtm1b(NCOM)Mfgc/Scribtm1b(NCOM)Mfgc Genetic Background: C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp
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MP:0005201 | abnormal retinal pigment epithelium morphology | "anomaly in the epithelial layer of the retina composed of cells containing pigment granules " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1tm1a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi
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MP:0005287 | narrow eye opening | "less than the normal distance from one eyelid to the other " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:71350] |
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Allelic Composition: Smoc1tm1b(EUCOMM)Wtsi/Smoc1tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H
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MP:0005430 | absent fibula | "missing the lateral and shorter of the two bones of the lower leg" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:86196] |
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Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1tm1a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi
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MP:0006221 | optic nerve hypoplasia | "less than the normal number of fibers in the optic nerve" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1tm1a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi
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MP:0006243 | abnormal pupil dilation reaction to light | "the pupil fails to constrict fully when exposed to bright light" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Smoc1tm1b(EUCOMM)Wtsi/Smoc1tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H
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MP:0006309 | decreased retinal ganglion cell number | "reduced number of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0008259 | abnormal optic disc morphology | "any structural anomaly of the area in the retina where all of the axons of the ganglion cells exit the retina to form the optic nerve" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Smoc1tm1b(EUCOMM)Wtsi/Smoc1tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H
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MP:0009874 | abnormal interdigital cell death | "change in the expected number of cells undergoing programmed cell death (apoptosis) in the autopod during development, precluding the sculpting of normal digits" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0010097 | abnormal retinal blood vessel morphology | "any structural anomaly of the blood vessels supplying the retina" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Smoc1tm1b(EUCOMM)Wtsi/Smoc1tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H
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MP:0010714 | coloboma of the iris | "congenital defect of the iris in which some part of the structure is absent" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1tm1a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi
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MP:0010715 | coloboma of the retina | "congenital defect of the retina in which some part of the structure is absent" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1tm1a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi
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MP:0010772 | abnormal pollex morphology | "any structural anomaly of the first or primary digit on the radial side of the hand" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Vil1-cre)997Gum/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1tm1a(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi
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MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Smoc1tm1b(EUCOMM)Wtsi/Smoc1tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H
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