ENSMUSG00000021188


Mus musculus

Features
Gene ID: ENSMUSG00000021188
  
Biological name :Trip11
  
Synonyms : thyroid hormone receptor interactor 11 / Trip11
  
Possible biological names infered from orthology : Q15643
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: E
Gene start: 101834043
Gene end: 101913267
  
Corresponding Affymetrix probe sets: 10402225 (MoGene1.0st)   1427406_at (Mouse Genome 430 2.0 Array)   1427407_s_at (Mouse Genome 430 2.0 Array)   1443975_at (Mouse Genome 430 2.0 Array)   1444042_at (Mouse Genome 430 2.0 Array)   1447973_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000134976
Ensembl peptide - ENSMUSP00000135128
Ensembl peptide - ENSMUSP00000135669
Ensembl peptide - ENSMUSP00000021605
Ensembl peptide - ENSMUSP00000134992
NCBI entrez gene - 109181     See in Manteia.
MGI - MGI:1924393
RefSeq - XM_011243986
RefSeq - NM_028446
RefSeq - XM_006515382
RefSeq - XM_006515383
RefSeq Peptide - NP_082722
swissprot - E9Q512
swissprot - Q8BVJ9
swissprot - H3BJH8
swissprot - H3BJU5
swissprot - H3BJG4
Ensembl - ENSMUSG00000021188
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trip11ENSDARG00000078381Danio rerio
 TRIP11ENSGALG00000010763Gallus gallus
 Q15643ENSG00000100815Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000237  GRIP domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003281 ventricular septum development IMP
 biological_processGO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis IMP
 biological_processGO:0006486 protein glycosylation IMP
 biological_processGO:0007030 Golgi organization IMP
 biological_processGO:0060122 inner ear receptor cell stereocilium organization IMP
 biological_processGO:0060348 bone development IMP
 cellular_componentGO:0002079 inner acrosomal membrane ISO
 cellular_componentGO:0002080 acrosomal membrane IDA
 cellular_componentGO:0002081 outer acrosomal membrane ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005801 cis-Golgi network IDA
 cellular_componentGO:0016607 nuclear speck ISO
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Intraflagellar transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000060 delayed bone ossification "late onset of the formation of bone" [J:40203]
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Allelic Composition: Tg(EIIa-cre)C5379Lmgd/?,Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

 MP:0000131 abnormal long bone epiphysis morphology "the head of a developing long bone that is separated from the shaft by the epiphyseal plate" [J:61509]
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Allelic Composition: Jak2tm1.1Jlvl/Jak2tm1.1Jlvl
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0000166 abnormal chondrocyte morphology "anomalous structure, organization, or differentiation of nondividing cartilage cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
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Allelic Composition: Jak2tm1.1Jlvl/Jak2tm1.1Jlvl
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Tg(EIIa-cre)C5379Lmgd/?,Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

 MP:0000273 overriding aorta "congenitally mispositioned aorta where the origin straddles the ventral septum and so receives ejected blood from the right ventricle as well as the left." [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cml, J:67826]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0000428 abnormal craniofacial morphology "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0000440 domed skull 
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Allelic Composition: Jak2tm1.1Jlvl/Jak2tm1.1Jlvl
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Tg(EIIa-cre)C5379Lmgd/?,Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

 MP:0000445 short snout "reduced length of the anterior facial part of the muzzle" [J:53370]
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Allelic Composition: Jak2tm1.1Jlvl/Jak2tm1.1Jlvl
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

 MP:0000457 maxilla hypoplasia "arrested growth or atrophy of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637]
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Allelic Composition: Tg(EIIa-cre)C5379Lmgd/?,Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

 MP:0000547 short limbs "reduced average length of the extremities" [MGI:CLS, J:61509]
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Allelic Composition: Jak2tm1.1Jlvl/Jak2tm1.1Jlvl
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trip11m1Mawa/Trip11m1Mawa,Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw
Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N

Allelic Composition: Tg(EIIa-cre)C5379Lmgd/?,Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
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Allelic Composition: Trip11m1Mawa/Trip11m1Mawa,Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw
Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N

 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Trip11m1Mawa/Trip11m1Mawa,Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw
Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Tg(EIIa-cre)C5379Lmgd/?,Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0001575 cyanosis "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mtcl1tm1.1Atsuz/Mtcl1tm1.1Atsuz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6JJcl

Allelic Composition: Bhlha15tm3(cre/ERT2)Skz/?,Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002270 abnormal alveoli morphology "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Jak2tm1.1Jlvl/Jak2tm1.1Jlvl
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002273 abnormal alveolar epithelial cell morphology "any structural anomaly of the cells lining the alveoli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0002274 abnormal type I pneumocyte morphology "any structural anomaly of the epithelial cells lining the alveoli through which gas exchange occurs; these are thin cells with a large surface area" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0002657 chondrodystrophy "abnormal development of the cartilage primordia of long bones, resulting in abnormally short extremities but normal head and trunk" [il:Ira Lu , Mouse Genome Informatics Curator]
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Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

 MP:0002741 small olfactory bulb "reduced size of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [J:79871]
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Allelic Composition: Trip11m1Mawa/Trip11m1Mawa,Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw
Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N

 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Jak2tm1.1Jlvl/Jak2tm1.1Jlvl
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002953 thick ventricular wall "increased depth of the cardiac wall of the heart ventricles" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0003052 omphalocele "protrusion of abdominal viscera at the base of the umbilical cord, with a covering membranous sac of peritoneum-amnion" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

Allelic Composition: Trip11m1Mawa/Trip11m1Mawa
Genetic Background: C57BL/6J-Trip11m1Mawa

Allelic Composition: Trip11m1Mawa/Trip11m1Mawa,Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw
Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N

 MP:0003419 delayed endochondral bone ossification "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]
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Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

 MP:0004007 abnormal lung vasculature "malformation or disorganization of the blood vessels of the lung" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0004686 decreased length of long bones "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

 MP:0004704 short vertebral column "decreased rostral-caudal length of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tg(EIIa-cre)C5379Lmgd/?,Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

 MP:0004986 abnormal osteoblast morphology "any structural anomaly of a bone-forming cell, which normally forms an osseous matrix (osteoid) in which it becomes enclosed as an osteocyte" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trip11m1Mawa/Trip11m1Mawa
Genetic Background: C57BL/6J-Trip11m1Mawa

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Jak2tm1.1Jlvl/Jak2tm1.1Jlvl
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0006027 impaired alveologenesis "a block or reduction in the generation of alveoli" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:85546]
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Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

 MP:0008274 failure of bone ossification "failure to initiate or a block in the process of the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503]
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Allelic Composition: Trip11m1Mawa/Trip11m1Mawa
Genetic Background: C57BL/6J-Trip11m1Mawa

 MP:0008546 abnormal vesicle-mediated transport "anomaly in the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell" [GO:0016192]
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Allelic Composition: Sox10tm1Weg/Sox10+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H

 MP:0009378 abnormal endoplasmic reticulum morphology "any structural anomaly of irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells" [GO:0005783]
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Allelic Composition: Trip11m1Mawa/Trip11m1Mawa
Genetic Background: C57BL/6J-Trip11m1Mawa

Allelic Composition: Tg(EIIa-cre)C5379Lmgd/?,Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

 MP:0009431 decreased fetal weight "reduced weight of a fetus compared to controls (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0009780 abnormal chondrocyte physiology "any functional anomaly of nondividing cartilage cells" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Trip11m1Mawa/Trip11m1Mawa
Genetic Background: C57BL/6J-Trip11m1Mawa

 MP:0009908 protruding tongue "the tongue extends out beyond the oral cavity past the lips; may be due to paralysis, oral cavity size, tongue hypoplasia or dysfunction of the hypoglossal nerve" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tg(EIIa-cre)C5379Lmgd/?,Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

 MP:0010103 small thoracic cage "reduced size of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trip11m1Mawa/Trip11m1Mawa
Genetic Background: C57BL/6J-Trip11m1Mawa

Allelic Composition: Tg(EIIa-cre)C5379Lmgd/?,Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

 MP:0010420 muscular ventricular septal defect "abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along the RV-septal junction; any single defect observed from the LV aspect may have several openings on the RV aspect" [http://emedicine.medscape.com]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0010449 heart right ventricle outflow tract stenosis "abnormal constriction or narrowing of part of the anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0010825 abnormal lung saccule morphology "any structural anomaly of the transient dilations of the developing alveolar (or transient) ducts, which transform into a transitory alveolar duct as soon as it develops further branches; the last transitory saccule formed on each pathway is a terminal saccule that develops into an alveolar sac after birth" [GO:0060430, ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0010827 small lung saccule "reduced size of the transient dilations of the developing alveolar (or transient) ducts, which transform into a transitory alveolar duct as soon as it develops further branches; the last transitory saccule formed on each pathway is a terminal saccule that develops into an alveolar sac after birth" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Trip11m1Mawa/Trip11m1Mawa,Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw
Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh,SordC57BL/Lia/SordC57BL/Lia
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/LiA

Allelic Composition: Trip11m1Mawa/Trip11m1Mawa
Genetic Background: C57BL/6J-Trip11m1Mawa

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

 MP:0011743 abnormal Golgi apparatus morphology "any structural anomaly of the compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack; Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations" [GO:0005794, MGI:mberry]
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Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(BGLAP-cre)1Clem/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/NJ

 MP:0020138 delayed bone mineralization "late onset of the process by which minerals are deposited into bone" [ORCID: orcid.org/0000-0003-4606-0597]
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Allelic Composition: Tg(EIIa-cre)C5379Lmgd/?,Trip11tm1.2Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N

Allelic Composition: Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?,Tg(Col2a1-cre)1Bhr/?,Trip11tm1.1Psmi/Trip11tm1.2Psmi
Genetic Background: involves: 129/Sv * C57BL/6 * SJL/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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