ENSMUSG00000021377


Mus musculus

Features
Gene ID: ENSMUSG00000021377
  
Biological name :Dek
  
Synonyms : Dek / Protein DEK / Q7TNV0
  
Possible biological names infered from orthology : DEK proto-oncogene / P35659
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A5
Gene start: 47084775
Gene end: 47106201
  
Corresponding Affymetrix probe sets: 10409031 (MoGene1.0st)   1443364_at (Mouse Genome 430 2.0 Array)   1452659_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021807
Ensembl peptide - ENSMUSP00000153538
Ensembl peptide - ENSMUSP00000121663
Ensembl peptide - ENSMUSP00000114392
NCBI entrez gene - 110052     See in Manteia.
MGI - MGI:1926209
RefSeq - NM_025900
RefSeq Peptide - NP_080176
swissprot - D3YVJ6
swissprot - A0A286YDS8
swissprot - E9Q8Y1
swissprot - Q7TNV0
Ensembl - ENSMUSG00000021377
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dekENSDARG00000070108Danio rerio
 DEKENSGALG00000012684Gallus gallus
 DEKENSG00000124795Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003034  SAP domain
 IPR014876  DEK, C-terminal
 IPR036361  SAP domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling IBA
 biological_processGO:2000779 regulation of double-strand break repair IEA
 biological_processGO:2001032 regulation of double-strand break repair via nonhomologous end joining IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0043292 contractile fiber IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0042393 histone binding IEA


Pathways (from Reactome)
Pathway description
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004502 decreased incidence of chemically-induced tumors "lower than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+,Pdgfratm12Sor/Pdgfra+
Genetic Background: involves: 129 * 129/Sv * C57BL/6J * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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