ENSMUSG00000021518


Mus musculus

Features
Gene ID: ENSMUSG00000021518
  
Biological name :Ptdss1
  
Synonyms : Phosphatidylserine synthase 1 / Ptdss1 / Q99LH2
  
Possible biological names infered from orthology : P48651
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: B3
Gene start: 66932830
Gene end: 66998401
  
Corresponding Affymetrix probe sets: 10405894 (MoGene1.0st)   1416372_at (Mouse Genome 430 2.0 Array)   1441866_s_at (Mouse Genome 430 2.0 Array)   1449739_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021990
Ensembl peptide - ENSMUSP00000153610
Ensembl peptide - ENSMUSP00000153371
Ensembl peptide - ENSMUSP00000153296
NCBI entrez gene - 19210     See in Manteia.
MGI - MGI:1276575
RefSeq - NM_008959
RefSeq Peptide - NP_032985
swissprot - A0A286YDD2
swissprot - A0A286YD63
swissprot - A0A286YDW7
swissprot - Q99LH2
Ensembl - ENSMUSG00000021518
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptdss1bENSDARG00000102114Danio rerio
 Q803C9ENSDARG00000012588Danio rerio
 si:dkey-108k24.2ENSDARG00000098729Danio rerio
 PTDSS1ENSGALG00000030185Gallus gallus
 P48651ENSG00000156471Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ptdss2 / Q9Z1X2 / Phosphatidylserine synthase 2 / Q9BVG9*ENSMUSG0000002549528


Protein motifs (from Interpro)
Interpro ID Name
 IPR004277  Phosphatidyl serine synthase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006659 phosphatidylserine biosynthetic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PS


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000194 hypercalcemia "abnormally high concentration of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0004777 abnormal phospholipid level "anomalous concentration of the fat derivatives in which one fatty acid has been replaced by a phosphate group" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Mta2tm1.1Yzha/Mta2tm1.1Yzha
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Ptdss1tm1Jev/Ptdss1+,Ptdss2Gt(KST314)Byg/Ptdss2Gt(KST314)Byg
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6

Allelic Composition: Ptdss1tm1Jev/Ptdss1tm1Jev,Ptdss2Gt(KST314)Byg/Ptdss2+
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6

 MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Mta2tm1.1Yzha/Mta2tm1.1Yzha
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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