ENSMUSG00000025495


Mus musculus

Features
Gene ID: ENSMUSG00000025495
  
Biological name :Ptdss2
  
Synonyms : Phosphatidylserine synthase 2 / Ptdss2 / Q9Z1X2
  
Possible biological names infered from orthology : Q9BVG9
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F5
Gene start: 141122382
Gene end: 141157606
  
Corresponding Affymetrix probe sets: 10558811 (MoGene1.0st)   1426728_x_at (Mouse Genome 430 2.0 Array)   1429492_x_at (Mouse Genome 430 2.0 Array)   1434586_a_at (Mouse Genome 430 2.0 Array)   1434587_x_at (Mouse Genome 430 2.0 Array)   1439984_at (Mouse Genome 430 2.0 Array)   1450354_a_at (Mouse Genome 430 2.0 Array)   1453164_a_at (Mouse Genome 430 2.0 Array)   1458387_at (Mouse Genome 430 2.0 Array)   1460010_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133352
Ensembl peptide - ENSMUSP00000134176
Ensembl peptide - ENSMUSP00000147593
Ensembl peptide - ENSMUSP00000026568
Ensembl peptide - ENSMUSP00000133804
NCBI entrez gene - 27388     See in Manteia.
MGI - MGI:1351664
RefSeq - XM_017322296
RefSeq - NM_013782
RefSeq - XM_006536196
RefSeq - XM_006536197
RefSeq - XM_006536198
RefSeq Peptide - NP_038810
swissprot - Q9Z1X2
swissprot - G3UXS3
swissprot - G3UYQ3
swissprot - G3UWN0
swissprot - A0A1B0GRN3
Ensembl - ENSMUSG00000025495
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 E7EY42ENSDARG00000101018Danio rerio
 PTDSS2ENSGALG00000004300Gallus gallus
 PTDSS2ENSG00000174915Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ptdss1 / Q99LH2 / Phosphatidylserine synthase 1 / P48651*ENSMUSG0000002151828


Protein motifs (from Interpro)
Interpro ID Name
 IPR004277  Phosphatidyl serine synthase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006659 phosphatidylserine biosynthetic process IMP
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity IMP
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PS


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Snai2tm1Look/Snai2tm1Look
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001152 Leydig cell hyperplasia "increased number of interstitial cells of the seminiferous tubules that secrete testosterone" [J:45065]
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Allelic Composition: Snai2tm1Look/Snai2tm1Look
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001750 increased circulating follicle stimulating hormone level "higher than normal levels in the blood stream of FSH, the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [J:35782, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Snai2tm1Look/Snai2tm1Look
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Snai2tm1Look/Snai2tm1Look
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003205 testicular atrophy "wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Snai2tm1Look/Snai2tm1Look
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004777 abnormal phospholipid level "anomalous concentration of the fat derivatives in which one fatty acid has been replaced by a phosphate group" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mta2tm1.1Yzha/Mta2tm1.1Yzha
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Ptdss1tm1Jev/Ptdss1tm1Jev,Ptdss2Gt(KST314)Byg/Ptdss2+
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Snai2tm1Look/Snai2tm1Look
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Mta2tm1.1Yzha/Mta2tm1.1Yzha
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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