ENSMUSG00000021556


Mus musculus

Features
Gene ID: ENSMUSG00000021556
  
Biological name :Golm1
  
Synonyms : golgi membrane protein 1 / Golm1 / Q91XA2
  
Possible biological names infered from orthology : Q8NBJ4
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B2
Gene start: 59634626
Gene end: 59675811
  
Corresponding Affymetrix probe sets: 10409767 (MoGene1.0st)   10338854 (MoGene1.0st)   10339134 (MoGene1.0st)   10339491 (MoGene1.0st)   10339559 (MoGene1.0st)   10339649 (MoGene1.0st)   10340202 (MoGene1.0st)   10340502 (MoGene1.0st)   10341100 (MoGene1.0st)   10341325 (MoGene1.0st)   10342764 (MoGene1.0st)   10342889 (MoGene1.0st)   10343496 (MoGene1.0st)   10343752 (MoGene1.0st)   10338883 (MoGene1.0st)   10343501 (MoGene1.0st)   10344462 (MoGene1.0st)   1415698_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022039
Ensembl peptide - ENSMUSP00000093410
NCBI entrez gene - 105348     See in Manteia.
MGI - MGI:1917329
RefSeq - NM_001035122
RefSeq - NM_027307
RefSeq Peptide - NP_001030294
RefSeq Peptide - NP_081583
swissprot - Q91XA2
Ensembl - ENSMUSG00000021556
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:56525ENSDARG00000025858Danio rerio
 GOLM1ENSGALG00000012601Gallus gallus
 GOLM1ENSG00000135052Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Casc4 / Q6P2L7 / Protein CASC4 / Q6P4E1* / cancer susceptibility 4*ENSMUSG0000006022723


Protein motifs (from Interpro)
Interpro ID Name
 IPR026139  GOLM1/CASC4 family
 IPR026143  Golgi membrane protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006997 nucleus organization IMP
 biological_processGO:0019216 regulation of lipid metabolic process IMP
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000607 abnormal hepatocyte morphology "malformation of the main structural component of the liver; these are specialized epithelial cells normally organize into interconnected plates called lobules" [J:23170, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0001859 kidney inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0001860 liver inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0002828 abnormal glomerular capsule "anomalous structure or development of the expanded beginning of a nephron that contains the glomerulus" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0004756 abnormal proximal convoluted tubule morphology "any structural anomaly of the convoluted portion of the duct system of the nephron that extends from the renal glomeurlar capsule in the kidney cortex into the kidney medulla where it joins the loop of Henle; fluid entering the proximal convoluted tubule is reabsorbed into the peritubular capillaries, including approximately two-thirds of the filtered salt and water and all filtered organic solutes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0004969 pale kidney "kidney lacks normal reddish coloration; often occurs with a bloodless or reduced vasculature condition" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0004970 kidney atrophy "wasting of the kidney due to injury or disease, resulting in reduced size" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0005202 lethargy "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0005264 glomerulosclerosis "hyaline deposits or scarring within the renal glomeruli, often occurring with renal arteriosclerosis or diabetes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0010179 rough coat "coat does not have the usual smooth appearance" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0011294 renal glomerulus hypertrophy "increase in the bulk size of the capillary loops of the kidney that normally function as a filtration unit, due to cell enlargement" [MGI:anna]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0011402 renal cast "any of the various casts formed from gelled protein precipitated in the distal convoluted tubules and collecting ducts of nephrons and molded to the tubular or duct lumen which dislodge and pass into the urine; types named for their constituent material include acellular casts (e.g. granular, hyaline, waxy, or fatty casts) and cellular casts (e.g. red or white blood cell casts)" [MGI:anna]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0011508 glomerular capillary thrombosis "formation or presence of a thrombus within the renal glomerular capillaries" [MGI:anna]
Show

Allelic Composition: Gt(ROSA)26Sortm2(SNCA*119)Djmo/Gt(ROSA)26Sor+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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