ENSMUSG00000021650


Mus musculus

Features
Gene ID: ENSMUSG00000021650
  
Biological name :Ptcd2
  
Synonyms : Pentatricopeptide repeat-containing protein 2, mitochondrial / Ptcd2 / Q8R3K3
  
Possible biological names infered from orthology : pentatricopeptide repeat domain 2 / Q8WV60
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: D1
Gene start: 99319647
Gene end: 99344705
  
Corresponding Affymetrix probe sets: 10411508 (MoGene1.0st)   1423769_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022153
NCBI entrez gene - 68927     See in Manteia.
MGI - MGI:1916177
RefSeq - NM_026873
RefSeq Peptide - NP_081149
swissprot - Q8R3K3
Ensembl - ENSMUSG00000021650
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptcd2ENSDARG00000035391Danio rerio
 PTCD2ENSGALG00000038260Gallus gallus
 PTCD2ENSG00000049883Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002885  Pentatricopeptide repeat
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR034629  Pentatricopeptide repeat-containing protein 2, mitochondrial
 IPR034913  MRPS27/PTCD2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0001889 liver development IMP
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007005 mitochondrion organization IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0048747 muscle fiber development IMP
 biological_processGO:0050684 regulation of mRNA processing IMP
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis IMP
 cellular_componentGO:0005739 mitochondrion ISO
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000278 abnormal myocardial fiber morphology "malformed or poorly developed cardiac muscle fibers, the multinucleated muscle cells of the heart" [J:18048]
Show

Allelic Composition: Adarb1tm1.1Eme/Adarb1tm1.1Eme
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0000280 thin ventricular wall "decreased depth of the cardiac wall of the heart ventricles" [J:45302]
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Allelic Composition: Adarb1tm1.1Eme/Adarb1tm1.1Eme
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0000598 abnormal liver morphology "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170]
Show

Allelic Composition: Adarb1tm1.1Eme/Adarb1tm1.1Eme
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Adarb1tm1.1Eme/Adarb1tm1.1Eme
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0002703 abnormal renal tubules "anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Adarb1tm1.1Eme/Adarb1tm1.1Eme
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0003068 enlarged kidney "larger than average size of the kidney" [J:86005, pvb:Pierre Vanden Borre, Mouse Genome Informatics Curator]
Show

Allelic Composition: Adarb1tm1.1Eme/Adarb1tm1.1Eme
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0004121 abnormal sarcolemma morphology "structural anomaly in the plasma membrane of a muscle fiber that is cabable of conducting electrical impuses" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Adarb1tm1.1Eme/Adarb1tm1.1Eme
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0004566 myocardial fiber degeneration "deterioration or destruction of cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Adarb1tm1.1Eme/Adarb1tm1.1Eme
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0005294 abnormal heart ventricle morphology "structural anomaly of one or both of the two lower chambers of the heart " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Adarb1tm1.1Eme/Adarb1tm1.1Eme
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0006035 abnormal mitochondrial morphology "anomalous structure of the mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Adarb1tm1.1Eme/Adarb1tm1.1Eme
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0010956 abnormal mitochondrial ATP synthesis coupled electron transport "anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV" [GO:0042775, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Adarb1tm1.1Eme/Adarb1tm1.1Eme
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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