Manteia

ENSMUSG00000021751

Mus musculus

Features

Gene ID:	ENSMUSG00000021751

Biological name :	Acox2

Synonyms :	Acox2 / Peroxisomal acyl-coenzyme A oxidase 2 / Q9QXD1

Possible biological names infered from orthology :	acyl-CoA oxidase 2 / Q99424

Species:	Mus musculus

Chr. number:	14
Strand:	-1
Band:	A1
Gene start:	8225511
Gene end:	8259353

Corresponding Affymetrix probe sets:	10417544 (MoGene1.0st) 1420673_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000022271 Ensembl peptide - ENSMUSP00000126464 Ensembl peptide - ENSMUSP00000130543 NCBI entrez gene - 93732 See in Manteia. MGI - MGI:1934852 RefSeq - XM_006518108 RefSeq - NM_001161667 RefSeq - NM_053115 RefSeq Peptide - NP_001155139 RefSeq Peptide - NP_444345 swissprot - Q9QXD1 swissprot - E9Q5T5 Ensembl - ENSMUSG00000021751

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Acox1 / Q9R0H0 / Peroxisomal acyl-coenzyme A oxidase 1 / Q15067* / acyl-CoA oxidase 1*	ENSMUSG00000020777	43
Acox3 / Q9EPL9 / Mus musculus acyl-Coenzyme A oxidase 3, pristanoyl (Acox3), transcript variant 3, mRNA. / O15254* / acyl-CoA oxidase 3, pristanoyl*	ENSMUSG00000029098	28
Acoxl / Q9DBS4 / Acyl-coenzyme A oxidase-like protein / Q9NUZ1* / acyl-CoA oxidase like*	ENSMUSG00000027380	23

Protein motifs (from Interpro)

Interpro ID	Name
IPR002655	Acyl-CoA oxidase, C-terminal
IPR006091	Acyl-CoA oxidase/dehydrogenase, central domain
IPR009100	Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
IPR012258	Acyl-CoA oxidase
IPR029320	Acyl-coenzyme A oxidase, N-terminal
IPR034171	Peroxisomal acyl-coenzyme A oxidase
IPR036250	Acyl-CoA dehydrogenase-like, C-terminal
IPR037069	Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006629	lipid metabolic process	IEA
biological_process	GO:0006631	fatty acid metabolic process	IEA
biological_process	GO:0006635	fatty acid beta-oxidation	IEA
biological_process	GO:0008152	metabolic process	IEA
biological_process	GO:0010942	positive regulation of cell death	IEA
biological_process	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	IBA
biological_process	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	IEA
biological_process	GO:0055114	oxidation-reduction process	IEA
biological_process	GO:1902884	positive regulation of response to oxidative stress	IEA
cellular_component	GO:0005777	peroxisome	ISO
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0043231	intracellular membrane-bounded organelle	IEA
molecular_function	GO:0003995	acyl-CoA dehydrogenase activity	IBA
molecular_function	GO:0003997	acyl-CoA oxidase activity	IEA
molecular_function	GO:0005102	signaling receptor binding	IEA
molecular_function	GO:0016491	oxidoreductase activity	IEA
molecular_function	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEA
molecular_function	GO:0033791	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity	ISO
molecular_function	GO:0042803	protein homodimerization activity	ISS
molecular_function	GO:0050660	flavin adenine dinucleotide binding	IEA
molecular_function	GO:0071949	FAD binding	IEA

Pathways (from Reactome)

Pathway description

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Cep290^{Gt(CC0582)Wtsi}/Cep290^{Gt(CC0582)Wtsi} Genetic Background: 129P2/OlaHsd-Cep290^{Gt(CC0582)Wtsi}

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr