MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0002644 | decreased circulating triglyceride level | "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0002702 | decreased circulating free fatty acid level | "lower than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0002891 | increased insulin sensitivity | "greater ability to clear glucose from the bloodstream when given insulin than normal; can result in hypoglycemia" [RGD:Rat Genome Database submission] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0002970 | abnormal white fat morphology | "structural aberration in the connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0004892 | increased adiponectin level | "greater level of a protein hormone that regulates glucose homeostasis and metabolism of lipids; it is normally produced by adipose tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0004953 | decreased spleen weight | "reduction in the average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0005289 | increased oxygen consumption | "greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0005334 | abnormal fat pad | "malformed or aberrant size of the encapsulated adipose tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0005668 | decreased circulating leptin level | "less than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0006094 | adipocyte hypertrophy | "increase in the size of fat cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:90802] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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MP:0011940 | decreased food intake | "reduction in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith] |
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N
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