ENSMUSG00000022236


Mus musculus

Features
Gene ID: ENSMUSG00000022236
  
Biological name :Ropn1l
  
Synonyms : Q9EQ00 / Ropn1l / Ropporin-1-like protein
  
Possible biological names infered from orthology : Q96C74 / rhophilin associated tail protein 1 like
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: B2
Gene start: 31441211
Gene end: 31453737
  
Corresponding Affymetrix probe sets: 10428012 (MoGene1.0st)   1423959_at (Mouse Genome 430 2.0 Array)   1457627_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000106038
NCBI entrez gene - 252967     See in Manteia.
MGI - MGI:2182357
RefSeq - NM_145852
RefSeq Peptide - NP_665851
swissprot - Q9EQ00
Ensembl - ENSMUSG00000022236
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q66IC9ENSDARG00000058370Danio rerio
 ROPN1LENSGALG00000013006Gallus gallus
 Q96C74ENSG00000145491Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ropn1 / Q9ESG2 / Ropporin-1 / Q9HAT0* / ROPN1B* / Q9BZX4* / rhophilin associated tail protein 1* / rhophilin associated tail protein 1B*ENSMUSG0000002283240


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IMP
 biological_processGO:0003341 cilium movement IMP
 biological_processGO:0030317 flagellated sperm motility IMP
 biological_processGO:0048240 sperm capacitation IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031514 motile cilium IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Sox10Dom/Sox10Dom
Genetic Background: involves: C3HeB/FeJLe * C57BL/6JLe

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Ropn1Gt(OST21705)Lex/Ropn1Gt(OST21705)Lex,Ropn1lGt(OST20298)Lex/Ropn1lGt(OST20298)Lex
Genetic Background: involves: 129S5/SvEvBrd

 MP:0004174 abnormal spine curvature "deviation from the typical S-shape of the spine" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

 MP:0011055 abnormal respiratory motile cilium physiology "any functional anomaly of the multiple epithelial tiny, motile hair-like projections, which have a variable arrangement of axonemal microtubules, contains molecular motors, and beat with a characteristic whip-like pattern that promote transport of fluids and other cells across the epithelium of the respiratory tract; may include alterations in ciliary beating pattern or frequency" [GO:0031514, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Sox10Dom/Sox10Dom
Genetic Background: involves: C3HeB/FeJLe * C57BL/6JLe

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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