ENSMUSG00000022832


Mus musculus

Features
Gene ID: ENSMUSG00000022832
  
Biological name :Ropn1
  
Synonyms : Q9ESG2 / Ropn1 / Ropporin-1
  
Possible biological names infered from orthology : Q9BZX4 / Q9HAT0 / rhophilin associated tail protein 1 / rhophilin associated tail protein 1B / ROPN1B
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: B3
Gene start: 34649921
Gene end: 34678618
  
Corresponding Affymetrix probe sets: 10435321 (MoGene1.0st)   1422543_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122122
Ensembl peptide - ENSMUSP00000023530
NCBI entrez gene - 76378     See in Manteia.
MGI - MGI:1923628
RefSeq - NM_030744
RefSeq - XM_006522698
RefSeq Peptide - NP_109669
swissprot - D3Z184
swissprot - Q9ESG2
Ensembl - ENSMUSG00000022832
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9BZX4ENSG00000114547Homo sapiens
 ROPN1ENSG00000065371Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9EQ00 / Ropn1l / Ropporin-1-like protein / Q96C74* / rhophilin associated tail protein 1 like*ENSMUSG0000002223642


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IMP
 biological_processGO:0030317 flagellated sperm motility IMP
 biological_processGO:0044782 cilium organization IGI
 biological_processGO:0048240 sperm capacitation IMP
 biological_processGO:0061512 protein localization to cilium IGI
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0097228 sperm principal piece IDA
 cellular_componentGO:0097598 sperm cytoplasmic droplet IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Sox10Dom/Sox10Dom
Genetic Background: involves: C3HeB/FeJLe * C57BL/6JLe

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Sox10Dom/Sox10Dom
Genetic Background: involves: C3HeB/FeJLe * C57BL/6JLe

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sox10Dom/Sox10Dom
Genetic Background: involves: C3HeB/FeJLe * C57BL/6JLe

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sox10Dom/Sox10Dom
Genetic Background: involves: C3HeB/FeJLe * C57BL/6JLe

Allelic Composition: Ropn1Gt(OST21705)Lex/Ropn1Gt(OST21705)Lex,Ropn1lGt(OST20298)Lex/Ropn1lGt(OST20298)Lex
Genetic Background: involves: 129S5/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022580 Rhpn1 / Q61085 / Rhophilin-1 / Q8TCX5* / rhophilin Rho GTPase binding protein 1*  / complex / reaction
 ENSMUSG00000007815 Rhoa / Q9QUI0 / ras homolog family member A / P61586*  / reaction / complex
 ENSMUSG00000022832 Ropn1 / Q9ESG2 / Ropporin-1 / Q9HAT0* / ROPN1B* / Q9BZX4* / rhophilin associated tail protein 1* / rhophilin associated tail protein 1B*  / complex






 

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