ENSMUSG00000022270


Mus musculus

Features
Gene ID: ENSMUSG00000022270
  
Biological name :Fam134b
  
Synonyms : Fam134b / Q8VE91 / Reticulophagy regulator 1
  
Possible biological names infered from orthology : Q9H6L5 / RETREG1
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: B1
Gene start: 25843180
Gene end: 25973687
  
Corresponding Affymetrix probe sets: 10423333 (MoGene1.0st)   1424683_at (Mouse Genome 430 2.0 Array)   1450505_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022881
Ensembl peptide - ENSMUSP00000106068
Ensembl peptide - ENSMUSP00000154070
Ensembl peptide - ENSMUSP00000154377
Ensembl peptide - ENSMUSP00000154407
Ensembl peptide - ENSMUSP00000154471
Ensembl peptide - ENSMUSP00000154765
Ensembl peptide - ENSMUSP00000154791
NCBI entrez gene - 66270     See in Manteia.
MGI - MGI:1913520
RefSeq - XM_017316720
RefSeq - NM_001034851
RefSeq - NM_001277315
RefSeq - NM_001277316
RefSeq - NM_001277317
RefSeq - NM_001277318
RefSeq - NM_025459
RefSeq - XM_006520134
RefSeq Peptide - NP_079735
RefSeq Peptide - NP_001264246
RefSeq Peptide - NP_001264247
RefSeq Peptide - NP_001264245
RefSeq Peptide - NP_001264244
RefSeq Peptide - NP_001030023
swissprot - Q8VE91
Ensembl - ENSMUSG00000022270
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 retreg1ENSDARG00000079059Danio rerio
 RETREG1ENSGALG00000042679Gallus gallus
 Q9H6L5ENSG00000154153Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9CQV4 / Retreg3 / Reticulophagy regulator 3 / Q86VR2* / reticulophagy regulator family member 3*ENSMUSG0000001780231
Q6NS82 / Retreg2 / Reticulophagy regulator 2 / Q8NC44* / reticulophagy regulator family member 2*ENSMUSG0000004933924


Protein motifs (from Interpro)
Interpro ID Name
 IPR033358  Reticulophagy receptor 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0019233 sensory perception of pain ISS
 biological_processGO:0043524 negative regulation of neuron apoptotic process IMP
 biological_processGO:0061709 reticulophagy IEA
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005801 cis-Golgi network IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016604 nuclear body ISO
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000965 abnormal sensory neuron morphology "malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of sensory impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
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Allelic Composition: Sod2tm1Kskk/Sod2tm1Kskk,Tg(BEST1-rtTA,tetO-cre)1Yzl/0
Genetic Background: B6J.Cg-Sod2tm1Kskk Tg(BEST1-rtTA,tetO-cre)1Yzl

 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
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Allelic Composition: Sod2tm1Kskk/Sod2tm1Kskk,Tg(BEST1-rtTA,tetO-cre)1Yzl/0
Genetic Background: B6J.Cg-Sod2tm1Kskk Tg(BEST1-rtTA,tetO-cre)1Yzl

 MP:0003224 neuron degeneration "a retrogressive impairment of function or destruction of the functional cells of the nervous system that receive, conduct, and transmit impulses " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Sod2tm1Kskk/Sod2tm1Kskk,Tg(BEST1-rtTA,tetO-cre)1Yzl/0
Genetic Background: B6J.Cg-Sod2tm1Kskk Tg(BEST1-rtTA,tetO-cre)1Yzl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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