ENSMUSG00000022564


Mus musculus

Features
Gene ID: ENSMUSG00000022564
  
Biological name :Grina
  
Synonyms : Grina / Protein lifeguard 1 / Q9ESF4
  
Possible biological names infered from orthology : glutamate ionotropic receptor NMDA type subunit associated protein 1 / Q7Z429
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: D3
Gene start: 76246764
Gene end: 76249904
  
Corresponding Affymetrix probe sets: 10424781 (MoGene1.0st)   1417423_at (Mouse Genome 430 2.0 Array)   1436297_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023225
Ensembl peptide - ENSMUSP00000154982
Ensembl peptide - ENSMUSP00000155539
Ensembl peptide - ENSMUSP00000155771
NCBI entrez gene - 66168     See in Manteia.
MGI - MGI:1913418
RefSeq - XM_011245709
RefSeq - NM_023168
RefSeq - XM_006521250
RefSeq - XM_006521251
RefSeq - XM_006521249
RefSeq Peptide - NP_075657
swissprot - Q9ESF4
Ensembl - ENSMUSG00000022564
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grinaaENSDARG00000101317Danio rerio
 GRINAENSG00000178719Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tmbim1 / transmembrane BAX inhibitor motif containing 1 / Q969X1*ENSMUSG0000000630137
Faim2 / Q8K097 / Protein lifeguard 2 / Q9BWQ8* / Fas apoptotic inhibitory molecule 2*ENSMUSG0000002301136
Tmbim7 / transmembrane BAX inhibitor motif containing 7ENSMUSG0000001452926
Q9DA39 / Tmbim4 / transmembrane BAX inhibitor motif containing 4 / Q9HC24* / AC078927.1*ENSMUSG0000002022523


Protein motifs (from Interpro)
Interpro ID Name
 IPR006214  Bax inhibitor 1-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis IDA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IGI
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0044325 ion channel binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lrp1tm2Her/Lrp1tm2Her,Tg(Camk2a-cre)T29-1Stl/0
Genetic Background: involves: 129S7/SvEvBrd * BALB/c * C57BL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr