ENSMUSG00000022621


Mus musculus

Features
Gene ID: ENSMUSG00000022621
  
Biological name :Rabl2
  
Synonyms : E9Q9D5 / Rabl2 / Rab-like protein 2A
  
Possible biological names infered from orthology : Q9UBK7 / Q9UNT1 / RABL2A / RABL2B / RAB, member of RAS oncogene family like 2A / RAB, member of RAS oncogene family like 2B
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E3
Gene start: 89582533
Gene end: 89591923
  
Corresponding Affymetrix probe sets: 10431612 (MoGene1.0st)   1431931_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000091598
Ensembl peptide - ENSMUSP00000129660
Ensembl peptide - ENSMUSP00000129253
Ensembl peptide - ENSMUSP00000129221
Ensembl peptide - ENSMUSP00000128799
Ensembl peptide - ENSMUSP00000126182
Ensembl peptide - ENSMUSP00000023294
NCBI entrez gene - 68708     See in Manteia.
MGI - MGI:1915958
RefSeq - XM_011245717
RefSeq - NM_026817
RefSeq - XM_006521326
RefSeq - XM_006521327
RefSeq - XM_006521329
RefSeq Peptide - NP_081093
swissprot - E9Q9D5
swissprot - E9Q8G6
swissprot - E9Q0F8
swissprot - E9PZU3
swissprot - F6Y6I9
swissprot - E9Q473
Ensembl - ENSMUSG00000022621
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rabl2ENSDARG00000063321Danio rerio
 RABL2LENSGALG00000032458Gallus gallus
 Q9UBK7ENSG00000144134Homo sapiens
 Q9UNT1ENSG00000079974Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q61820 / Rasl2-9 / RAS-like, family 2, locus 9ENSMUSG0000008364926
Ran / P62827 / GTP-binding nuclear protein Ran ENSMUSG0000002943025
1700009N14Rik / RIKEN cDNA 1700009N14 gene / RAN* / P62826* / RAN, member RAS oncogene family*ENSMUSG0000002828725


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007338 single fertilization IMP
 biological_processGO:0008594 photoreceptor cell morphogenesis IMP
 biological_processGO:0030317 flagellated sperm motility IMP
 biological_processGO:0060271 cilium assembly IMP
 cellular_componentGO:0030992 intraciliary transport particle B IDA
 cellular_componentGO:0097225 sperm midpiece IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Col1a1tm1(tetO-CTNNB1)Tcd/Col1a1+,Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6J

Allelic Composition: Rabl2mot/Rabl2mot
Genetic Background: C57BL/6(CBA)-Rabl2mot

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col1a1tm1(tetO-CTNNB1)Tcd/Col1a1+,Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6J

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Col1a1tm1(tetO-CTNNB1)Tcd/Col1a1+,Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6J

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col1a1tm1(tetO-CTNNB1)Tcd/Col1a1+,Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6J

 MP:0009239 short sperm flagellum "decreased length of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col1a1tm1(tetO-CTNNB1)Tcd/Col1a1+,Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr