ENSMUSG00000028287


Mus musculus

Features
Gene ID: ENSMUSG00000028287
  
Biological name :1700009N14Rik
  
Synonyms : 1700009N14Rik / RIKEN cDNA 1700009N14 gene
  
Possible biological names infered from orthology : P62826 / RAN / RAN, member RAS oncogene family
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A5
Gene start: 39450295
Gene end: 39451776
  
Corresponding Affymetrix probe sets: 10503958 (MoGene1.0st)   1429747_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029955
NCBI entrez gene - 75471     See in Manteia.
MGI - MGI:1922721
RefSeq - NM_001081095
RefSeq Peptide - NP_001074564
swissprot - Q14AA6
Ensembl - ENSMUSG00000028287
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ranENSDARG00000057026Danio rerio
 RANENSGALG00000002569Gallus gallus
 RANENSG00000132341Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ran / P62827 / GTP-binding nuclear protein Ran ENSMUSG0000002943093
Q61820 / Rasl2-9 / RAS-like, family 2, locus 9ENSMUSG0000008364988
Rabl2 / E9Q9D5 / Rab-like protein 2A / RABL2A* / Q9UBK7* / Q9UNT1* / RABL2B* / RAB, member of RAS oncogene family like 2A* / RAB, member of RAS oncogene family like 2B*ENSMUSG0000002262125


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR002041  Ran GTPase
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000054 ribosomal subunit export from nucleus IBA
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0006913 nucleocytoplasmic transport IEA
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IBA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019904 protein domain specific binding IPI


Pathways (from Reactome)
Pathway description
Regulation of cholesterol biosynthesis by SREBP (SREBF)
Transcriptional regulation by small RNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000067150 Xpo5 / Q924C1 / exportin 5 / Q9HAV4*  / complex
 ENSMUSG00000020538 Q9WTN3 / Srebf1 / Mus musculus sterol regulatory element binding transcription factor 1 (Srebf1), transcript variant 4, mRNA. / P36956* / sterol regulatory element binding transcription factor 1*  / reaction
 ENSMUSG00000040029 Ipo8 / Q7TMY7 / Importin-8 / O15397*  / reaction / complex
 ENSMUSG00000034667 Xpot / Q9CRT8 / exportin, tRNA (nuclear export receptor for tRNAs) / O43592* / exportin for tRNA*  / complex
 ENSMUSG00000001440 Kpnb1 / P70168 / Importin subunit beta-1 / Q14974* / karyopherin subunit beta 1*  / complex / reaction
 ENSMUSG00000036698 Ago2 / Q8CJG0 / Protein argonaute-2 / Q9UKV8* / argonaute 2, RISC catalytic component*  / reaction
 ENSMUSG00000022463 Q3U1N2 / Srebf2 / sterol regulatory element binding factor 2 / Q12772* / sterol regulatory element binding transcription factor 2*  / reaction






 

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