ENSMUSG00000040029


Mus musculus

Features
Gene ID: ENSMUSG00000040029
  
Biological name :Ipo8
  
Synonyms : Importin-8 / Ipo8 / Q7TMY7
  
Possible biological names infered from orthology : O15397
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: G3
Gene start: 148770683
Gene end: 148831467
  
Corresponding Affymetrix probe sets: 10549447 (MoGene1.0st)   1426760_at (Mouse Genome 430 2.0 Array)   1452185_at (Mouse Genome 430 2.0 Array)   1459203_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117365
Ensembl peptide - ENSMUSP00000144744
Ensembl peptide - ENSMUSP00000046759
NCBI entrez gene - 320727     See in Manteia.
MGI - MGI:2444611
RefSeq - XM_006507065
RefSeq - XM_006507066
RefSeq - XM_017321649
RefSeq - NM_001081113
RefSeq Peptide - NP_001074582
swissprot - Q7TMY7
swissprot - A0A0N4SUM9
swissprot - B2KGD7
Ensembl - ENSMUSG00000040029
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ipo8ENSDARG00000058159Danio rerio
 IPO8ENSGALG00000012953Gallus gallus
 IPO8ENSG00000133704Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ipo7 / Q9EPL8 / Importin-7 / O95373*ENSMUSG0000006623263


Protein motifs (from Interpro)
Interpro ID Name
 IPR001494  Importin-beta, N-terminal domain
 IPR011989  Armadillo-like helical
 IPR013713  Exportin/Importin, Cse1-like
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005887 integral component of plasma membrane ISA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0008536 Ran GTPase binding IEA
 molecular_functionGO:0008565 protein transporter activity IBA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances ISA


Pathways (from Reactome)
Pathway description
Transcriptional regulation by small RNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028287 1700009N14Rik / RIKEN cDNA 1700009N14 gene / RAN* / P62826* / RAN, member RAS oncogene family*  / reaction / complex
 ENSMUSG00000036698 Ago2 / Q8CJG0 / Protein argonaute-2 / Q9UKV8* / argonaute 2, RISC catalytic component*  / complex / reaction






 

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contact: otassy@igbmc.fr