ENSG00000133704


Homo sapiens

Features
Gene ID: ENSG00000133704
  
Biological name :IPO8
  
Synonyms : importin 8 / IPO8 / O15397
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p11.21
Gene start: 30628988
Gene end: 30695986
  
Corresponding Affymetrix probe sets: 205701_at (Human Genome U133 Plus 2.0 Array)   225528_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000446254
Ensembl peptide - ENSP00000446232
Ensembl peptide - ENSP00000481026
Ensembl peptide - ENSP00000256079
Ensembl peptide - ENSP00000439413
Ensembl peptide - ENSP00000439556
Ensembl peptide - ENSP00000440979
Ensembl peptide - ENSP00000443789
Ensembl peptide - ENSP00000444050
Ensembl peptide - ENSP00000444520
NCBI entrez gene - 10526     See in Manteia.
OMIM - 605600
RefSeq - XM_017018692
RefSeq - NM_001190995
RefSeq - NM_006390
RefSeq - XM_017018691
RefSeq Peptide - NP_006381
RefSeq Peptide - NP_001177924
swissprot - F5H815
swissprot - H0YH64
swissprot - O15397
swissprot - A0A087WXH2
swissprot - F5GXT5
swissprot - F5H009
swissprot - F5H292
swissprot - F5H244
swissprot - F5H2I3
Ensembl - ENSG00000133704
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ipo8ENSDARG00000058159Danio rerio
 IPO8ENSGALG00000012953Gallus gallus
 Ipo8ENSMUSG00000040029Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IPO7 / O95373 / importin 7ENSG0000020533964


Protein motifs (from Interpro)
Interpro ID Name
 IPR001494  Importin-beta, N-terminal domain
 IPR011989  Armadillo-like helical
 IPR013713  Exportin/Importin, Cse1-like
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008536 Ran GTPase binding IEA
 molecular_functionGO:0008565 protein transporter activity IBA


Pathways (from Reactome)
Pathway description
Transcriptional regulation by small RNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000123908 AGO2 / Q9UKV8 / argonaute 2, RISC catalytic component  / complex / reaction
 ENSG00000132341 RAN / P62826 / RAN, member RAS oncogene family  / complex / reaction






 

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