ENSGALG00000002569


Gallus gallus

Features
Gene ID: ENSGALG00000002569
  
Biological name :RAN
  
Synonyms : GTP-binding nuclear protein Ran / P42558 / RAN
  
Possible biological names infered from orthology : 1700009N14Rik / P62826 / P62827 / Q61820 / RAN, member RAS oncogene family / Rasl2-9 / RAS-like, family 2, locus 9 / RIKEN cDNA 1700009N14 gene
  
Species: Gallus gallus
  
Chr. number: 15
Strand: -1
Band:
Gene start: 3200454
Gene end: 3205623
  
Corresponding Affymetrix probe sets: Gga.4068.1.S1_at (Chicken Array)   Gga.4068.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047624
Ensembl peptide - ENSGALP00000064376
Ensembl peptide - ENSGALP00000059301
Ensembl peptide - ENSGALP00000054241
Ensembl peptide - ENSGALP00000004046
NCBI entrez gene - 396193     See in Manteia.
RefSeq - NM_205258
RefSeq Peptide - NP_990589
swissprot - A0A1L1RZU0
swissprot - A0A1L1RKL2
swissprot - A0A1I7Q3Y7
swissprot - P42558
Ensembl - ENSGALG00000002569
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ranENSDARG00000057026Danio rerio
 RANENSG00000132341Homo sapiens
 1700009N14RikENSMUSG00000028287Mus musculus
 Q61820ENSMUSG00000083649Mus musculus
 RanENSMUSG00000029430Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RABL2L / Rabl2* / RABL2A* / RABL2B* / E9Q9D5* / Q9UBK7* / Q9UNT1* / Rab-like protein 2A * / RAB, member of RAS oncogene family like 2A* / RAB, member of RAS oncogene family like 2B*ENSGALG0000003245828


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR002041  Ran GTPase
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000054 ribosomal subunit export from nucleus IBA
 biological_processGO:0000055 ribosomal large subunit export from nucleus IEA
 biological_processGO:0000056 ribosomal small subunit export from nucleus IEA
 biological_processGO:0000060 protein import into nucleus, translocation IEA
 biological_processGO:0000070 mitotic sister chromatid segregation ISS
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0006611 protein export from nucleus IEA
 biological_processGO:0006913 nucleocytoplasmic transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0046039 GTP metabolic process ISS
 biological_processGO:0061015 snRNA import into nucleus ISS
 biological_processGO:1902570 protein localization to nucleolus IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0042565 RNA nuclear export complex IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISS
 molecular_functionGO:0003924 GTPase activity IBA
 molecular_functionGO:0005525 GTP binding ISS
 molecular_functionGO:0019003 GDP binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0070883 pre-miRNA binding IEA


Pathways (from Reactome)
Pathway description
Regulation of cholesterol biosynthesis by SREBP (SREBF)
Transcriptional regulation by small RNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010341 XPO5 / exportin 5 / Q924C1* / Q9HAV4*  / complex
 ENSGALG00000041687 SREBF2 / sterol regulatory element binding transcription factor 2 / Q12772* / Q3U1N2* / sterol regulatory element binding factor 2*  / reaction
 ENSGALG00000009835 XPOT / exportin for tRNA / O43592* / Q9CRT8* / exportin, tRNA (nuclear export receptor for tRNAs)*  / complex






 

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