ENSMUSG00000034667


Mus musculus

Features
Gene ID: ENSMUSG00000034667
  
Biological name :Xpot
  
Synonyms : exportin, tRNA (nuclear export receptor for tRNAs) / Q9CRT8 / Xpot
  
Possible biological names infered from orthology : exportin for tRNA / O43592
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D2
Gene start: 121587380
Gene end: 121626332
  
Corresponding Affymetrix probe sets: 10372877 (MoGene1.0st)   1428772_at (Mouse Genome 430 2.0 Array)   1428949_at (Mouse Genome 430 2.0 Array)   1441681_at (Mouse Genome 430 2.0 Array)   1441682_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151253
Ensembl peptide - ENSMUSP00000151828
Ensembl peptide - ENSMUSP00000151722
Ensembl peptide - ENSMUSP00000043488
NCBI entrez gene - 73192     See in Manteia.
MGI - MGI:1920442
RefSeq - XM_006514204
RefSeq - XM_006514206
RefSeq - XM_006514207
RefSeq - XM_006514208
RefSeq - NM_001081056
RefSeq Peptide - NP_001074525
swissprot - Q9CRT8
swissprot - A0A1W2P7Q6
swissprot - A0A1W2P6G8
swissprot - A0A1W2P7V1
Ensembl - ENSMUSG00000034667
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 xpotENSDARG00000099652Danio rerio
 XPOTENSGALG00000009835Gallus gallus
 XPOTENSG00000184575Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001494  Importin-beta, N-terminal domain
 IPR011989  Armadillo-like helical
 IPR013598  Exportin-1/Importin-beta-like
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006409 tRNA export from nucleus IEA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0071528 tRNA re-export from nucleus IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016363 nuclear matrix IBA
 molecular_functionGO:0000049 tRNA binding IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0008536 Ran GTPase binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ube2ctm1.1(KOMP)Wtsi/Ube2c+
Genetic Background: C57BL/6N-Ube2ctm1.1(KOMP)Wtsi/J

 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

Allelic Composition: Xpottm3b(EUCOMM)Hmgu/Xpot+
Genetic Background: C57BL/6N-Xpottm3b(EUCOMM)Hmgu/Bay

 MP:0003743 abnormal facial morphology "anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Xpottm3b(EUCOMM)Hmgu/Xpot+
Genetic Background: C57BL/6N-Xpottm3b(EUCOMM)Hmgu/Bay

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028287 1700009N14Rik / RIKEN cDNA 1700009N14 gene / RAN* / P62826* / RAN, member RAS oncogene family*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr