ENSG00000184575


Homo sapiens

Features
Gene ID: ENSG00000184575
  
Biological name :XPOT
  
Synonyms : exportin for tRNA / O43592 / XPOT
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q14.2
Gene start: 64404350
Gene end: 64451127
  
Corresponding Affymetrix probe sets: 212160_at (Human Genome U133 Plus 2.0 Array)   227117_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000327821
Ensembl peptide - ENSP00000383722
Ensembl peptide - ENSP00000441376
Ensembl peptide - ENSP00000444345
NCBI entrez gene - 11260     See in Manteia.
OMIM - 603180
RefSeq - XM_017018748
RefSeq - NM_007235
RefSeq Peptide - NP_009166
swissprot - F8WDU6
swissprot - F5GYW6
swissprot - O43592
swissprot - F5GZM3
Ensembl - ENSG00000184575
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 xpotENSDARG00000099652Danio rerio
 XPOTENSGALG00000009835Gallus gallus
 XpotENSMUSG00000034667Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001494  Importin-beta, N-terminal domain
 IPR011989  Armadillo-like helical
 IPR013598  Exportin-1/Importin-beta-like
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006409 tRNA export from nucleus IDA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0071528 tRNA re-export from nucleus IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016363 nuclear matrix IBA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0008536 Ran GTPase binding IEA


Pathways (from Reactome)
Pathway description
tRNA processing in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132341 RAN / P62826 / RAN, member RAS oncogene family  / complex / reaction






 

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contact: otassy@igbmc.fr