ENSMUSG00000022650


Mus musculus

Features
Gene ID: ENSMUSG00000022650
  
Biological name :Retnlb
  
Synonyms : resistin like beta / Retnlb
  
Possible biological names infered from orthology : Q9BQ08
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: B5
Gene start: 48816856
Gene end: 48818891
  
Corresponding Affymetrix probe sets: 10436087 (MoGene1.0st)   1418368_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023328
NCBI entrez gene - 57263     See in Manteia.
MGI - MGI:1888505
RefSeq - NM_023881
RefSeq Peptide - NP_076370
swissprot - A0A0R4J042
Ensembl - ENSMUSG00000022650
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9BQ08ENSG00000163515Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Retnlg / Q8K426 / Resistin-like gamma / Q9BQ08* / RETNLB* / resistin like beta*ENSMUSG0000002265167
Retnla / resistin like alpha / Q9BQ08* / RETNLB* / resistin like beta*ENSMUSG0000006110052
Retn / Q99P87 / resistin / Q9HD89*ENSMUSG0000001270536


Protein motifs (from Interpro)
Interpro ID Name
 IPR009714  Resistin
 IPR036262  Resistin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005179 hormone activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000488 abnormal intestinal epithelium morphology "anomalous structure or development of the cellular avascular layer of the digestive tube passing from the stomach to the anus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: MipCts/Mip+
Genetic Background: (CTA/Idr x MT/HokIdr)F1

 MP:0001663 abnormal digestive system physiology "altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: MipCts/Mip+
Genetic Background: (CTA/Idr x MT/HokIdr)F1

 MP:0001876 decreased inflammatory response "less than expected response to injury, infection, or insult" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Hrctm1Blk/Hrc+
Genetic Background: B6.129S6-Hrctm1Blk

 MP:0005026 decreased susceptibility to parasitic infection "reduced likelihood that an organism will develop ill effects from a parasitic infection or from components of or toxins produced by parasites " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Retnlbtm1Mer/Retnlbtm1Mer
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0005166 decreased susceptiblity to injury "less than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Hrctm1Blk/Hrc+
Genetic Background: B6.129S6-Hrctm1Blk

 MP:0008496 decreased IgG2a level "less than normal immunoglobulin class G2a level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Retnlbtm1Mer/Retnlbtm1Mer
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0008499 increased IgG1 level "greater than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Retnlbtm1Mer/Retnlbtm1Mer
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0008537 increased susceptibility to induced colitis "increased severity or induction threshold of colitis upon treatment of an organism with intestinal inflammation agents such as dextran sodium sulfate (DSS)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: MipCts/Mip+
Genetic Background: (CTA/Idr x MT/HokIdr)F1

 MP:0008539 decreased susceptibility to induced colitis "decreased severity or induction threshold of colitis upon treatment of an organism with intestinal inflammation agents such as dextran sodium sulfate (DSS)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hrctm1Blk/Hrc+
Genetic Background: B6.129S6-Hrctm1Blk

Allelic Composition: Retnlbtm1Mer/Retnlbtm1Mer
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0008561 decreased tumor necrosis factor secretion "reduction in the production or release of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MESH:D12.644.276.374.500.800]
Show

Allelic Composition: Retnlbtm1Mer/Retnlbtm1Mer
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0008567 decreased interferon-gamma secretion "reduction in the production or release of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" [MESH:D12.644.276.374.440.893]
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Allelic Composition: Retnlbtm1Mer/Retnlbtm1Mer
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0009764 decreased sensitivity to induced morbidity/mortality "increase in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hrctm1Blk/Hrc+
Genetic Background: B6.129S6-Hrctm1Blk

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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