ENSMUSG00000022871


Mus musculus

Features
Gene ID: ENSMUSG00000022871
  
Biological name :Fetub
  
Synonyms : Fetub / Fetuin-B / Q9QXC1
  
Possible biological names infered from orthology : Q9UGM5
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: B1
Gene start: 22918382
Gene end: 22939766
  
Corresponding Affymetrix probe sets: 10434698 (MoGene1.0st)   1449555_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023587
Ensembl peptide - ENSMUSP00000112324
Ensembl peptide - ENSMUSP00000128745
Ensembl peptide - ENSMUSP00000128989
NCBI entrez gene - 59083     See in Manteia.
MGI - MGI:1890221
RefSeq - XM_006522437
RefSeq - NM_001083904
RefSeq - NM_001083905
RefSeq - NM_021564
RefSeq Peptide - NP_001077374
RefSeq Peptide - NP_067539
RefSeq Peptide - NP_001077373
swissprot - Q6YJU1
swissprot - Q9QXC1
Ensembl - ENSMUSG00000022871
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fetubENSDARG00000053973Danio rerio
 si:ch211-284e20.8ENSDARG00000070918Danio rerio
 FETUBENSGALG00000008608Gallus gallus
 FETUBENSG00000090512Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ahsg / P29699 / Alpha-2-HS-glycoprotein / P02765*ENSMUSG0000002286821


Protein motifs (from Interpro)
Interpro ID Name
 IPR000010  Cystatin domain
 IPR001363  Proteinase inhibitor I25C, fetuin, conserved site
 IPR025764  Fetuin-B-type cystatin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007338 single fertilization IMP
 biological_processGO:0007339 binding of sperm to zona pellucida IMP
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004857 enzyme inhibitor activity IEA
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0008191 metalloendopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ttll5tm1.1N/Ttll5tm1.1N
Genetic Background: B6.Cg-Ttll5tm1.1N

Allelic Composition: Fetubtm1Wja/Fetubtm1Wja
Genetic Background: D2.Cg-Fetubtm1Wja

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Ttll5tm1.1N/Ttll5tm1.1N
Genetic Background: B6.Cg-Ttll5tm1.1N

Allelic Composition: Fetubtm1Wja/Fetubtm1Wja
Genetic Background: D2.Cg-Fetubtm1Wja

 MP:0003696 abnormal zona pellucida "anomaly or absence of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ttll5tm1.1N/Ttll5tm1.1N
Genetic Background: B6.Cg-Ttll5tm1.1N

Allelic Composition: Fetubtm1Wja/Fetubtm1Wja
Genetic Background: D2.Cg-Fetubtm1Wja

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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