Manteia

ENSMUSG00000022899

Mus musculus

Features

Gene ID:	ENSMUSG00000022899

Biological name :	Slc15a2

Synonyms :	Slc15a2 / solute carrier family 15 (H+/peptide transporter), member 2

Possible biological names infered from orthology :	Q16348 / solute carrier family 15 member 2

Species:	Mus musculus

Chr. number:	16
Strand:	-1
Band:	B3
Gene start:	36750178
Gene end:	36784962

Corresponding Affymetrix probe sets:	10439321 (MoGene1.0st) 1417600_at (Mouse Genome 430 2.0 Array) 1424730_a_at (Mouse Genome 430 2.0 Array) 1447808_s_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000023616 Ensembl peptide - ENSMUSP00000132885 Ensembl peptide - ENSMUSP00000132663 Ensembl peptide - ENSMUSP00000132029 Ensembl peptide - ENSMUSP00000131395 NCBI entrez gene - 57738 See in Manteia. MGI - MGI:1890457 RefSeq - XM_006522430 RefSeq - NM_001145899 RefSeq - NM_021301 RefSeq - XM_006522428 RefSeq Peptide - NP_001139371 RefSeq Peptide - NP_067276 swissprot - E9QMN8 swissprot - E9Q329 swissprot - E9Q0L2 swissprot - E9PYQ9 swissprot - G3XA51 Ensembl - ENSMUSG00000022899

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q9JIP7 / Slc15a1 / solute carrier family 15 (oligopeptide transporter), member 1 / P46059* / solute carrier family 15 member 1*	ENSMUSG00000025557	46
Q91W98 / Slc15a4 / Solute carrier family 15 member 4 / Q8N697*	ENSMUSG00000029416	17
Q8BPX9 / Slc15a3 / Solute carrier family 15 member 3 / Q8IY34*	ENSMUSG00000024737	17
Q8CBB2 / Slc15a5 / Solute carrier family 15 member 5 / A6NIM6*	ENSMUSG00000044378	14

Protein motifs (from Interpro)

Interpro ID	Name
IPR000109	Proton-dependent oligopeptide transporter family
IPR004768	Oligopeptide transporter
IPR018456	PTR2 family proton/oligopeptide symporter, conserved site
IPR020846	Major facilitator superfamily domain
IPR029028	Alpha/beta knot methyltransferases
IPR036259	MFS transporter superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006857	oligopeptide transport	IEA
biological_process	GO:0035672	oligopeptide transmembrane transport	IEA
biological_process	GO:0055085	transmembrane transport	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0005215	transporter activity	IEA
molecular_function	GO:0022857	transmembrane transporter activity	IEA
molecular_function	GO:0035673	oligopeptide transmembrane transporter activity	IEA

Pathways (from Reactome)

Pathway description

Proton/oligopeptide cotransporters

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0005621	abnormal cell physiology	"aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]	Show Allelic Composition: Foxn1^nu-str/Foxn1^nu-str Genetic Background: AKR/J-Foxn1^nu-str/J
MP:0010107	abnormal renal reabsorption	"any anomaly in the two-step process beginning with the active or passive extraction of substances (such as water, glucose, oligopeptides, amino acids, sodium (Na+) and other ions) from the renal tubule fluid into the renal interstitium, and the subsequent transport of these substances out of the renal interstitium back into the bloodstream; reabsorption begins in the proximal convoluted tubules and continues in the loop of Henle, distal convoluted tubules, and collecting tubules" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lyst^bg-slt/Lyst^bg-slt,Myo5a^d/Myo5a^d Genetic Background: involves: CT/Ch * YZ57/Ch
MP:0011445	abnormal renal protein reabsorption	"any anomaly in the process in which proteins are taken up from the collecting ducts and proximal and distal loops of the nephron" [GO:0097017]	Show Allelic Composition: Lyst^bg-slt/Lyst^bg-slt,Myo5a^d/Myo5a^d Genetic Background: involves: CT/Ch * YZ57/Ch

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr