ENSMUSG00000023022


Mus musculus

Features
Gene ID: ENSMUSG00000023022
  
Biological name :Lima1
  
Synonyms : Lima1 / LIM domain and actin-binding protein 1 / Q9ERG0
  
Possible biological names infered from orthology : LIM domain and actin binding 1 / Q9UHB6
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: F1
Gene start: 99778470
Gene end: 99875456
  
Corresponding Affymetrix probe sets: 10432540 (MoGene1.0st)   1422499_at (Mouse Genome 430 2.0 Array)   1425654_a_at (Mouse Genome 430 2.0 Array)   1435726_at (Mouse Genome 430 2.0 Array)   1435727_s_at (Mouse Genome 430 2.0 Array)   1450629_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000073371
Ensembl peptide - ENSMUSP00000104652
Ensembl peptide - ENSMUSP00000155772
NCBI entrez gene - 65970     See in Manteia.
MGI - MGI:1920992
RefSeq - XM_006521245
RefSeq - NM_001113545
RefSeq - NM_023063
RefSeq Peptide - NP_075550
RefSeq Peptide - NP_001107017
swissprot - Q8CD09
swissprot - Q9ERG0
Ensembl - ENSMUSG00000023022
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LIMA1ENSG00000050405Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Limd2 / Q8BGB5 / Mus musculus LIM domain containing 2 (Limd2), transcript variant 3, mRNA. / Q9BT23* / LIM domain containing 2*ENSMUSG000000406999


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type
 IPR028740  LIM domain and actin-binding protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030835 negative regulation of actin filament depolymerization ISS
 biological_processGO:0031529 ruffle organization IEA
 biological_processGO:0051017 actin filament bundle assembly ISO
 cellular_componentGO:0001725 stress fiber IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005903 brush border IDA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0032154 cleavage furrow IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0003785 actin monomer binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051015 actin filament binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000124 absent teeth "missing bony structures of the upper and lower jaws used in mastication" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
Show

Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H

 MP:0000432 abnormal head morphology "anomalous structure or development of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr