ENSMUSG00000023089


Mus musculus

Features
Gene ID: ENSMUSG00000023089
  
Biological name :Ndufa5
  
Synonyms : NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 / Ndufa5 / Q9CPP6
  
Possible biological names infered from orthology : NADH:ubiquinone oxidoreductase subunit A5 / Q16718
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: A3.1
Gene start: 24518666
Gene end: 24528013
  
Corresponding Affymetrix probe sets: 10543442 (MoGene1.0st)   1417285_a_at (Mouse Genome 430 2.0 Array)   1417286_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023851
Ensembl peptide - ENSMUSP00000112971
NCBI entrez gene - 68202     See in Manteia.
MGI - MGI:1915452
RefSeq - NM_001311068
RefSeq - NM_026614
RefSeq Peptide - NP_001297997
RefSeq Peptide - NP_080890
swissprot - Q9CPP6
swissprot - D3YTQ8
Ensembl - ENSMUSG00000023089
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ndufa5ENSDARG00000039346Danio rerio
 NDUFA5ENSGALG00000008821Gallus gallus
 NDUFA5ENSG00000128609Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006806  ETC complex I subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0022904 respiratory electron transport chain IMP
 biological_processGO:0032981 mitochondrial respiratory chain complex I assembly IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005747 mitochondrial respiratory chain complex I IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0045271 respiratory chain complex I IMP
 cellular_componentGO:0070469 respiratory chain IEA
 molecular_functionGO:0008137 NADH dehydrogenase (ubiquinone) activity IMP
 molecular_functionGO:0016651 oxidoreductase activity, acting on NAD(P)H IEA


Pathways (from Reactome)
Pathway description
Respiratory electron transport
Complex I biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Kif20b33cex/Kif20bmagoo
Genetic Background: involves: BALB/c * C3HeB/FeJ * C57BL/6 * FVB/N

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Kif20b33cex/Kif20bmagoo
Genetic Background: involves: BALB/c * C3HeB/FeJ * C57BL/6 * FVB/N

 MP:0005202 lethargy "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Kif20b33cex/Kif20bmagoo
Genetic Background: involves: BALB/c * C3HeB/FeJ * C57BL/6 * FVB/N

 MP:0010955 abnormal respiratory electron transport chain "anomaly in the process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient" [GO:0022904]
Show

Allelic Composition: Kif20b33cex/Kif20bmagoo
Genetic Background: involves: BALB/c * C3HeB/FeJ * C57BL/6 * FVB/N

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Kif20b33cex/Kif20bmagoo
Genetic Background: involves: BALB/c * C3HeB/FeJ * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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