ENSMUSG00000023150


Mus musculus

Features
Gene ID: ENSMUSG00000023150
  
Biological name :Ivns1abp
  
Synonyms : Influenza virus NS1A-binding protein homolog / Ivns1abp / Q920Q8
  
Possible biological names infered from orthology : influenza virus NS1A binding protein / Q9Y6Y0
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: G1
Gene start: 151344477
Gene end: 151364422
  
Corresponding Affymetrix probe sets: 10350594 (MoGene1.0st)   1420961_a_at (Mouse Genome 430 2.0 Array)   1425718_a_at (Mouse Genome 430 2.0 Array)   1450084_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000095150
Ensembl peptide - ENSMUSP00000140332
Ensembl peptide - ENSMUSP00000140708
Ensembl peptide - ENSMUSP00000023918
Ensembl peptide - ENSMUSP00000107518
NCBI entrez gene - 117198     See in Manteia.
MGI - MGI:2152389
RefSeq - XM_017322265
RefSeq - NM_001039511
RefSeq - NM_001039512
RefSeq - NM_054102
RefSeq - XM_006529088
RefSeq - XM_006529089
RefSeq Peptide - NP_473443
RefSeq Peptide - NP_001034600
RefSeq Peptide - NP_001034601
swissprot - Q920Q8
swissprot - A0A087WQT3
Ensembl - ENSMUSG00000023150
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ivns1abpbENSDARG00000013946Danio rerio
 Q5RG82ENSDARG00000031100Danio rerio
 ENSGALG00000045555Gallus gallus
 ENSGALG00000037162Gallus gallus
 Q9Y6Y0ENSG00000116679Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ipp / P28575 / Actin-binding protein IPP / Q9Y573* / intracisternal A particle-promoted polypeptide*ENSMUSG0000002869623
Klhl26 / Q8BGY4 / Kelch-like protein 26 / Q53HC5* / kelch like family member 26*ENSMUSG0000005570722
Klhl9 / Q6ZPT1 / Kelch-like protein 9 / Q9P2J3* / kelch like family member 9*ENSMUSG0000007092321
Klhl13 / Q80TF4 / Kelch-like protein 13 / Q9P2N7* / kelch like family member 13*ENSMUSG0000003678220
Klhl34 / kelch like family member 34 / Q8N239*ENSMUSG0000004748520
Klhl32 / kelch like family member 32 / Q96NJ5*ENSMUSG0000004038719
Gan / Q8CA72 / Gigaxonin / Q9H2C0*ENSMUSG0000005255719
Klhl22 / Q99JN2 / Mus musculus kelch-like 22 (Klhl22), transcript variant 2, mRNA. / Q53GT1* / kelch like family member 22*ENSMUSG0000002275019
Klhl31 / kelch like family member 31 / Q9H511*ENSMUSG0000004493819
Klhl7 / Q8BUL5 / kelch-like 7 / Q8IXQ5* / kelch like family member 7*ENSMUSG0000002898619
Klhl14 / Q69ZK5 / Kelch-like protein 14 / Q9P2G3* / kelch like family member 14*ENSMUSG0000004251418
Klhl36 / Q8R124 / Kelch-like protein 36 / Q8N4N3* / kelch like family member 36*ENSMUSG0000003182818
A2AAX3 / Klhl15 / Kelch-like protein 15 / Q96M94* / kelch like family member 15*ENSMUSG0000004392917
Klhl33 / kelch like family member 33 / A6NCF5*ENSMUSG0000009079915


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR029849  Influenza virus NS1A-binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003222 increased cardiomyocyte apoptosis "increase in the number of cardiac muscle cells undergoing programmed cell death" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0005140 decreased cardiac muscle contractility "inability or reduced ability of the heart muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0005324 ascites "accumulation or retention of fluid within the peritoneal cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0008873 increased sensitivity to xenobiotics "decrease in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0008943 increased sensitivity to induced cell death "decrease in the exposure level to an agent that is required to induce cessation of function at the cellular level" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0009766 increased sensitivity to xenobiotic induced morbidity/mortality "decrease in the amount of a foreign compound required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0010334 pleural effusion "accumulation of excess fluid in the pleural cavity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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