ENSMUSG00000023170


Mus musculus

Features
Gene ID: ENSMUSG00000023170
  
Biological name :Gps2
  
Synonyms : Gps2 / Mus musculus G protein pathway suppressor 2 (Gps2), transcript variant 2, mRNA. / Q921N8
  
Possible biological names infered from orthology : G protein pathway suppressor 2 / Q13227
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 69913888
Gene end: 69916591
  
Corresponding Affymetrix probe sets: 10377652 (MoGene1.0st)   1417796_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000054072
Ensembl peptide - ENSMUSP00000072389
Ensembl peptide - ENSMUSP00000112062
Ensembl peptide - ENSMUSP00000136921
NCBI entrez gene - 56310     See in Manteia.
MGI - MGI:1891751
RefSeq - XM_017314685
RefSeq - NM_001357906
RefSeq - NM_019726
RefSeq - XM_006533785
RefSeq - XM_006533787
RefSeq - XM_017314684
RefSeq Peptide - NP_001344835
RefSeq Peptide - NP_062700
swissprot - J3QNR4
swissprot - Q921N8
Ensembl - ENSMUSG00000023170
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gps2ENSDARG00000035558Danio rerio
 GPS2ENSG00000132522Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026094  G protein pathway suppressor 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0045599 negative regulation of fat cell differentiation IMP
 biological_processGO:0046329 negative regulation of JNK cascade ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0017053 transcriptional repressor complex ISO
 molecular_functionGO:0003714 transcription corepressor activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030332 cyclin binding ISO


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0006207 embryonic lethality during organogenesis "death anytime after embryo turning but before the completion of organogenesis (E9 to less than E14)" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Npytm1(cre)Zman/Npytm1(cre)Zman
Genetic Background: involves: 129/Sv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type






 

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contact: otassy@igbmc.fr