ENSMUSG00000023755


Mus musculus

Features
Gene ID: ENSMUSG00000023755
  
Biological name :Rhebl1
  
Synonyms : GTPase RhebL1 / Q9D8T3 / Rhebl1
  
Possible biological names infered from orthology : Q8TAI7 / RHEB like 1
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: F1
Gene start: 98877778
Gene end: 98894540
  
Corresponding Affymetrix probe sets: 10432362 (MoGene1.0st)   1447818_x_at (Mouse Genome 430 2.0 Array)   1451516_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000155216
Ensembl peptide - ENSMUSP00000024518
Ensembl peptide - ENSMUSP00000155010
Ensembl peptide - ENSMUSP00000155126
Ensembl peptide - ENSMUSP00000155149
NCBI entrez gene - 69159     See in Manteia.
MGI - MGI:1916409
RefSeq - NM_026967
RefSeq - XM_006521345
RefSeq Peptide - NP_081243
swissprot - Q9D8T3
Ensembl - ENSMUSG00000023755
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8TAI7ENSG00000167550Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rheb / Q921J2 / Ras homolog enriched in brain / Q15382* / Ras homolog, mTORC1 binding*ENSMUSG0000002894552


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0031929 TOR signaling IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Rheb*)Pfw/Gt(ROSA)26Sortm1(CAG-Rheb*)Pfw,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Il1r1tm1Imx/Il1r1tm1Imx
Genetic Background: B6.129-Il1r1tm1Imx Apoetm1Unc

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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