ENSMUSG00000024175


Mus musculus

Features
Gene ID: ENSMUSG00000024175
  
Biological name :Tekt4
  
Synonyms : Tekt4
  
Possible biological names infered from orthology : Q8WW24 / tektin 4
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A3.3
Gene start: 25471590
Gene end: 25476594
  
Corresponding Affymetrix probe sets: 10442807 (MoGene1.0st)   1453121_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025002
NCBI entrez gene - 71840     See in Manteia.
MGI - MGI:1919090
RefSeq - NM_027951
RefSeq - XM_006524948
RefSeq Peptide - NP_082227
swissprot - A0A0R4J051
Ensembl - ENSMUSG00000024175
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tekt4ENSDARG00000028899Danio rerio
 ENSGALG00000005247Gallus gallus
 TEKT4ENSG00000163060Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tekt3 / Q6X6Z7 / tektin 3 / Q9BXF9*ENSMUSG0000004218938
Tekt1 / Q9DAJ2 / Tektin-1 / Q969V4*ENSMUSG0000002079935
Tekt5 / G5E8A8 / Tektin-5 / Q96M29*ENSMUSG0000003917934
Tekt2 / Q922G7 / Mus musculus tektin 2 (Tekt2), transcript variant 2, mRNA. / Q9UIF3* / tektin 2*ENSMUSG0000002884529


Protein motifs (from Interpro)
Interpro ID Name
 IPR000435  Tektin


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast,Dicer1tm1Mmk/Dicer1tm1Mmk,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129S1/Sv * BALB/c

Allelic Composition: Tekt3tm1Zuk/Tekt3tm1Zuk,Tekt4tm1Zuk/Tekt4tm1Zuk
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast,Dicer1tm1Mmk/Dicer1tm1Mmk,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129S1/Sv * BALB/c

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast,Dicer1tm1Mmk/Dicer1tm1Mmk,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129S1/Sv * BALB/c

Allelic Composition: Tekt3tm1Zuk/Tekt3tm1Zuk,Tekt4tm1Zuk/Tekt4tm1Zuk
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0004543 abnormal sperm physiology "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast,Dicer1tm1Mmk/Dicer1tm1Mmk,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129S1/Sv * BALB/c

 MP:0008892 abnormal sperm flagellum "any strucutral anomaly of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MESH:A05.360.490.890.840]
Show

Allelic Composition: Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast,Dicer1tm1Mmk/Dicer1tm1Mmk,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129S1/Sv * BALB/c

 MP:0009831 abnormal sperm midpiece morphology "any structural abnormality of the highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece" [PMID:14581499]
Show

Allelic Composition: Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast,Dicer1tm1Mmk/Dicer1tm1Mmk,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129S1/Sv * BALB/c

 MP:0009836 abnormal sperm principal piece morphology "any structural abnormality in the segment of the sperm flagellum where the mitochondrial sheath ends and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs; the principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece" [PMID:14581499]
Show

Allelic Composition: Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast,Dicer1tm1Mmk/Dicer1tm1Mmk,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129S1/Sv * BALB/c

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr