ENSMUSG00000028845


Mus musculus

Features
Gene ID: ENSMUSG00000028845
  
Biological name :Tekt2
  
Synonyms : Mus musculus tektin 2 (Tekt2), transcript variant 2, mRNA. / Q922G7 / Tekt2
  
Possible biological names infered from orthology : Q9UIF3 / tektin 2
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D2.2
Gene start: 126322121
Gene end: 126325688
  
Corresponding Affymetrix probe sets: 10516335 (MoGene1.0st)   1418484_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116659
Ensembl peptide - ENSMUSP00000030658
Ensembl peptide - ENSMUSP00000099676
Ensembl peptide - ENSMUSP00000114688
NCBI entrez gene - 24084     See in Manteia.
MGI - MGI:1346335
RefSeq - XM_017320192
RefSeq - NM_001357262
RefSeq - NM_001357263
RefSeq - NM_011902
RefSeq - XM_017320190
RefSeq - XM_017320191
RefSeq Peptide - NP_001344192
RefSeq Peptide - NP_036032
RefSeq Peptide - NP_001344191
swissprot - A3KFY5
swissprot - Q922G7
swissprot - A3KFX9
Ensembl - ENSMUSG00000028845
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tekt2ENSDARG00000028973Danio rerio
 TEKT2ENSGALG00000002319Gallus gallus
 TEKT2ENSG00000092850Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tekt4 / Q8WW24* / tektin 4*ENSMUSG0000002417530
Tekt1 / Q9DAJ2 / Tektin-1 / Q969V4*ENSMUSG0000002079930
Tekt3 / Q6X6Z7 / tektin 3 / Q9BXF9*ENSMUSG0000004218929
Tekt5 / G5E8A8 / Tektin-5 / Q96M29*ENSMUSG0000003917928


Protein motifs (from Interpro)
Interpro ID Name
 IPR000435  Tektin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0030317 flagellated sperm motility IMP
 biological_processGO:0036159 inner dynein arm assembly IMP
 biological_processGO:0060294 cilium movement involved in cell motility IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0036126 sperm flagellum IBA
 cellular_componentGO:0042995 cell projection IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Cacna2d2tm1Svi/Cacna2d2tm1Svi
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0001947 abnormal mucociliary clearance "anomaly in the rate of ciliary and secretory activity of the respiratory submucosal glands" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cacna2d2tm1Svi/Cacna2d2tm1Svi
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0002285 abnormal tracheal ciliated epithelium morphology "structural anomaly of the epithelial lining of the trachea which contains numerous ciliated cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology:ISBN 0-397-51047-0]
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Allelic Composition: Cacna2d2tm1Svi/Cacna2d2tm1Svi
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Cacna2d2tm1Svi/Cacna2d2tm1Svi
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0009243 hairpin sperm flagellum "a structural alteration where the sperm flagellum becomes bent back (folded) on itself to form a hairpin (loop) structure; a sharp hairpin-like bend formation can disrupt the axial structures and cause the sperm tail to become kinked" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cacna2d2tm1Svi/Cacna2d2tm1Svi
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0009838 abnormal sperm axoneme morphology "any structural abnormality of the central core of the sperm flagellum, composed of a ring of 9 outer microtubule doublets surrounding a central pair; inner and outer dynein arms project from each of the outer 9 doublets, and these arms are responsible for generating the motive force of the flagellum; in addition, 9 radial spokes, each of which originates from 1 of the 9 outer microtubular doublet pairs, project inward toward the central pair in a helical fashion" [PMID:14581499]
Show

Allelic Composition: Cacna2d2tm1Svi/Cacna2d2tm1Svi
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0011050 abnormal respiratory motile cilium morphology "any structural anomaly of the multiple epithelial tiny, motile hair-like projections, which have a variable arrangement of axonemal microtubules, contains molecular motors, and beat with a characteristic whip-like pattern that promote transport of fluids and other cells across the epithelium of the respiratory tract" [GO:0031514, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cacna2d2tm1Svi/Cacna2d2tm1Svi
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0011055 abnormal respiratory motile cilium physiology "any functional anomaly of the multiple epithelial tiny, motile hair-like projections, which have a variable arrangement of axonemal microtubules, contains molecular motors, and beat with a characteristic whip-like pattern that promote transport of fluids and other cells across the epithelium of the respiratory tract; may include alterations in ciliary beating pattern or frequency" [GO:0031514, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cacna2d2tm1Svi/Cacna2d2tm1Svi
Genetic Background: involves: 129S1/Sv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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