ENSMUSG00000024480


Mus musculus

Features
Gene ID: ENSMUSG00000024480
  
Biological name :Ap3s1
  
Synonyms : AP-3 complex subunit sigma-1 / Ap3s1 / Q9DCR2
  
Possible biological names infered from orthology : adaptor related protein complex 3 sigma 1 subunit / Q92572
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: C
Gene start: 46741876
Gene end: 46790826
  
Corresponding Affymetrix probe sets: 10455542 (MoGene1.0st)   10574096 (MoGene1.0st)   10604230 (MoGene1.0st)   1422593_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000153510
Ensembl peptide - ENSMUSP00000153557
Ensembl peptide - ENSMUSP00000025357
Ensembl peptide - ENSMUSP00000153290
Ensembl peptide - ENSMUSP00000153388
NCBI entrez gene - 11777     See in Manteia.
MGI - MGI:1337062
RefSeq - XM_006525528
RefSeq - XM_006525526
RefSeq - NM_001303015
RefSeq - NM_009681
RefSeq Peptide - NP_033811
RefSeq Peptide - NP_001289944
swissprot - Q3U8S0
swissprot - Q9DCR2
swissprot - A0A286YDU3
swissprot - A0A286YD58
Ensembl - ENSMUSG00000024480
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AP3S1ENSGALG00000002341Gallus gallus
 AP3S1ENSG00000177879Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ap3s2 / Q8BSZ2 / AP-3 complex subunit sigma-2 / P59780* / adaptor related protein complex 3 sigma 2 subunit*ENSMUSG0000006380183


Protein motifs (from Interpro)
Interpro ID Name
 IPR000804  Clathrin adaptor complex, small chain
 IPR011012  Longin-like domain superfamily
 IPR016635  Adaptor protein complex, sigma subunit
 IPR022775  AP complex, mu/sigma subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0008089 anterograde axonal transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0048490 anterograde synaptic vesicle transport IMP
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030123 AP-3 adaptor complex IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0008565 protein transporter activity IEA


Pathways (from Reactome)
Pathway description
Golgi Associated Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002626 increased heart rate "greater than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Anks6tm1b(KOMP)Wtsi/Anks6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Anks6tm1b(KOMP)Wtsi/Wtsi

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
Show

Allelic Composition: Anks6tm1b(KOMP)Wtsi/Anks6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Anks6tm1b(KOMP)Wtsi/Wtsi

 MP:0013279 increased fasted circulating glucose level "increase in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
Show

Allelic Composition: Anks6tm1b(KOMP)Wtsi/Anks6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Anks6tm1b(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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