ENSMUSG00000063801


Mus musculus

Features
Gene ID: ENSMUSG00000063801
  
Biological name :Ap3s2
  
Synonyms : AP-3 complex subunit sigma-2 / Ap3s2 / Q8BSZ2
  
Possible biological names infered from orthology : adaptor related protein complex 3 sigma 2 subunit / P59780
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: D2
Gene start: 79875325
Gene end: 79920649
  
Corresponding Affymetrix probe sets: 10564839 (MoGene1.0st)   1422718_at (Mouse Genome 430 2.0 Array)   1428044_at (Mouse Genome 430 2.0 Array)   1435718_at (Mouse Genome 430 2.0 Array)   1436525_at (Mouse Genome 430 2.0 Array)   1441993_at (Mouse Genome 430 2.0 Array)   1444413_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146264
Ensembl peptide - ENSMUSP00000075082
NCBI entrez gene - 11778     See in Manteia.
MGI - MGI:1337060
RefSeq - NM_009682
RefSeq Peptide - NP_033812
swissprot - A0A0U1RQ64
swissprot - Q8BSZ2
Ensembl - ENSMUSG00000063801
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ap3s2ENSDARG00000039882Danio rerio
 AP3S2ENSGALG00000008291Gallus gallus
 AP3S2ENSG00000157823Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ap3s1 / Q9DCR2 / AP-3 complex subunit sigma-1 / Q92572* / adaptor related protein complex 3 sigma 1 subunit*ENSMUSG0000002448083


Protein motifs (from Interpro)
Interpro ID Name
 IPR000804  Clathrin adaptor complex, small chain
 IPR011012  Longin-like domain superfamily
 IPR016635  Adaptor protein complex, sigma subunit
 IPR022775  AP complex, mu/sigma subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport TAS
 biological_processGO:0008089 anterograde axonal transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport TAS
 biological_processGO:0048490 anterograde synaptic vesicle transport IMP
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030123 AP-3 adaptor complex IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:1904115 axon cytoplasm IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Anks6tm1b(KOMP)Wtsi/Anks6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Anks6tm1b(KOMP)Wtsi/Wtsi

 MP:0003382 straub tail "condition in which an animal carries its tail in an erect (vertical or nearly vertical) position; often seen upon opioid and other drug treatment" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Anks6tm1b(KOMP)Wtsi/Anks6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Anks6tm1b(KOMP)Wtsi/Wtsi

 MP:0005343 increased circulating aspartate transaminase level "greater than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]
Show

Allelic Composition: Anks6tm1b(KOMP)Wtsi/Anks6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Anks6tm1b(KOMP)Wtsi/Wtsi

 MP:0010088 decreased circulating fructosamine level "decrease in the concentration in the blood of total non enzymatic glycated proteins in the blood" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Anks6tm1b(KOMP)Wtsi/Anks6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Anks6tm1b(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr