ENSMUSG00000024519


Mus musculus

Features
Gene ID: ENSMUSG00000024519
  
Biological name :Cplx4
  
Synonyms : Complexin-4 / Cplx4 / Q80WM3
  
Possible biological names infered from orthology : Q7Z7G2
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: E1
Gene start: 65955727
Gene end: 65970178
  
Corresponding Affymetrix probe sets: 10459475 (MoGene1.0st)   1451590_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025397
NCBI entrez gene - 225644     See in Manteia.
MGI - MGI:2685803
RefSeq - NM_145493
RefSeq Peptide - NP_663468
swissprot - Q80WM3
Ensembl - ENSMUSG00000024519
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cplx4aENSDARG00000059978Danio rerio
 cplx4bENSDARG00000059486Danio rerio
 CPLX4ENSGALG00000038426Gallus gallus
 CPLX4ENSG00000166569Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cplx3 / Q8R1B5 / Complexin-3 / Q8WVH0*ENSMUSG0000003971463


Protein motifs (from Interpro)
Interpro ID Name
 IPR008849  Synaphin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0046928 regulation of neurotransmitter secretion IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IDA
 molecular_functionGO:0000149 SNARE binding IDA
 molecular_functionGO:0019905 syntaxin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001004 abnormal photoreceptor morphology "structural or developmental anomaly of the receptors sensitive to light " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Aifm1tm2.1Pngr/Aifm1tm2.1Pngr
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0002090 abnormal vision "inability or decreased ability to see " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Aifm1tm2.1Pngr/Aifm1tm2.1Pngr
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Aifm1tm2.1Pngr/Aifm1tm2.1Pngr
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: Aifm1tm2.1Pngr/Aifm1tm2.1Pngr
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cplx3tm1Rmnd/Cplx3tm1Rmnd,Cplx4tm1Bros/Cplx4tm1Bros
Genetic Background: involves: C57BL/6

 MP:0008520 disorganized retinal outer plexiform layer "a derangement of the normal pattern of the retinal layer that is the site of synapses between the rods and cones (axons) and the horizontal and bipolar cells (dendrites)" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cplx3tm1Rmnd/Cplx3tm1Rmnd,Cplx4tm1Bros/Cplx4tm1Bros
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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