ENSMUSG00000024646


Mus musculus

Features
Gene ID: ENSMUSG00000024646
  
Biological name :Cyb5a
  
Synonyms : Cyb5a / Cytochrome b5 / P56395
  
Possible biological names infered from orthology : cytochrome b5 type A / P00167
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: E4
Gene start: 84851338
Gene end: 84880401
  
Corresponding Affymetrix probe sets: 10457071 (MoGene1.0st)   1416727_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124480
Ensembl peptide - ENSMUSP00000025549
Ensembl peptide - ENSMUSP00000124412
NCBI entrez gene - 109672     See in Manteia.
MGI - MGI:1926952
RefSeq - NM_025797
RefSeq - XM_017317803
RefSeq Peptide - NP_080073
RefSeq Peptide - NP_001335088
swissprot - G5E850
swissprot - P56395
swissprot - Q544Z9
swissprot - E0CY88
Ensembl - ENSMUSG00000024646
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyb5aENSDARG00000098589Danio rerio
 CYB5AENSGALG00000013708Gallus gallus
 CYB5AENSG00000166347Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cyb5b / Q9CQX2 / Cytochrome b5 type B / O43169*ENSMUSG0000003192445


Protein motifs (from Interpro)
Interpro ID Name
 IPR001199  Cytochrome b5-like heme/steroid binding domain
 IPR018506  Cytochrome b5, heme-binding site
 IPR036400  Cytochrome b5-like heme/steroid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006631 fatty acid metabolic process IC
 biological_processGO:0046686 response to cadmium ion IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004768 stearoyl-CoA 9-desaturase activity TAS
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Vitamin C (ascorbate) metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008875 abnormal pharmacokinetics of xenobiotics "any anomaly in the absorbtion, distribution, metabolism or elimination of a foreign compound" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Cyb5atm1Wolf/Cyb5atm1Wolf,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000018042 Cyb5r3 / Q9DCN2 / NADH-cytochrome b5 reductase 3 NADH-cytochrome b5 reductase 3 membrane-bound form NADH-cytochrome b5 reductase 3 soluble form / P00387* / cytochrome b5 reductase 3*  / reaction






 

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