ENSMUSG00000024941


Mus musculus

Features
Gene ID: ENSMUSG00000024941
  
Biological name :Scyl1
  
Synonyms : N-terminal kinase-like protein / Q9EQC5 / Scyl1
  
Possible biological names infered from orthology : Q96KG9 / SCY1 like pseudokinase 1
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 5758427
Gene end: 5771401
  
Corresponding Affymetrix probe sets: 10465226 (MoGene1.0st)   1430354_x_at (Mouse Genome 430 2.0 Array)   1436804_s_at (Mouse Genome 430 2.0 Array)   1451051_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025890
NCBI entrez gene - 78891     See in Manteia.
MGI - MGI:1931787
RefSeq - XM_006531857
RefSeq - NM_023912
RefSeq - XM_006531856
RefSeq Peptide - NP_076401
swissprot - Q9EQC5
Ensembl - ENSMUSG00000024941
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scyl1ENSDARG00000079854Danio rerio
 SCYL1ENSG00000142186Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Scyl3 / Q9DBQ7 / Protein-associating with the carboxyl-terminal domain of ezrin / Q8IZE3* / SCY1 like pseudokinase 3*ENSMUSG0000002658417


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment ISS
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005801 cis-Golgi network IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0030126 COPI vesicle coat IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0000750 abnormal muscle regeneration "inability or defects in ability to repair muscle after injuries" [J:42574]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0000752 dystrophic muscle "progressive weakness and wasting of muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67994]
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Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0000755 hindlimb paralysis "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0000849 abnormal cerebellum morphology "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0000864 abnormal vermis "malformation in the narrow middle zone between the two hemispheres of the cerebellum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61509]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0000877 abnormal Purkinje cell "any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0000880 decreased Purkinje cell number "fewer than normal neuronal cells that are located in the interface of the molecular and granular layers of the cerebellar cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:45302]
Show

Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0000921 demyelination "loss of the myelin sheath without loss of axons or fiber tracts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0000937 abnormal motor neuron morphology "malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of motor impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
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Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0000938 motor neuron degeneration "retrogressive impairment of function or destruction of the cells that innervate an effector (muscle or glandular) tissue" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0000939 reduced motor neuron number "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Scyl1tm1Spel/Scyl1tm1Spel,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0000958 peripheral nervous system degeneration "a retrogressive impairment of function or destruction of the ganglia and peripheral nerves that lie outside the brain and spinal cord" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Scyl1mdf/Scyl1mdf
Genetic Background: involves: CFW * C57BL/6J * C57BR

 MP:0001052 abnormal muscle innervation "malfomation or misprojection of sensory or motor nerves to targets in muscle" [J:75958]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0001053 abnormal neuromuscular synapse "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]
Show

Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Pknox1tm2.1Fbla/Pknox1tm2.1Fbla,Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Scyl1tm1Spel/Scyl1tm1Spel,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0001330 abnormal optic nerve morphology "malformation, misprojection or atrophy in the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0001388 abnormal stationary movement "altered ability or inability to change body posture or shift a body part" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0001391 abnormal tail movements "a change from the normal manner of moving the tail" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0001392 abnormal locomotor activity "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Scyl1tm1Spel/Scyl1tm1Spel,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Scyl1tm1Spel/Scyl1tm1Spel,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0001921 reduced fertility "diminished ability to produce live offspring" [J:65030]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pknox1tm2.1Fbla/Pknox1tm2.1Fbla,Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Scyl1tm1Spel/Scyl1tm1Spel,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pknox1tm2.1Fbla/Pknox1tm2.1Fbla,Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd

 MP:0002184 abnormal innervation "the malformation, misprojection or malfunction of the connection of nerve fibers with a target" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0002269 muscular atrophy "a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

Allelic Composition: Scyl1mdf/Scyl1mdf
Genetic Background: involves: CFW * C57BL/6J * C57BR

Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0002752 abnormal somatic nervous system morphology "malformation or absence of any of the cranial and spinal nerves or their ganglia or the peripheral sensory receptors" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Scyl1mdf/Scyl1mdf
Genetic Background: involves: CFW * C57BL/6J * C57BR

 MP:0003312 abnormal locomotor coordination "reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Scyl1tm1Spel/Scyl1tm1Spel,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0003354 astrocytosis "a proliferation or spread of astrocytes in the area of a degenerative lesion or damaged tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Scyl1tm1Spel/Scyl1tm1Spel,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0003492 abnormal involuntary movement "anomalies in movements that occur independent of planning (eg. reflexive behavior)" [Nmice:Neuromice Consortium Submission]
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Allelic Composition: Scyl1mdf/Scyl1mdf
Genetic Background: involves: CFW * C57BL/6J * C57BR

 MP:0003633 abnormal nervous system physiology 
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Allelic Composition: Scyl1mdf/Scyl1mdf
Genetic Background: involves: CFW * C57BL/6J * C57BR

 MP:0003871 abnormal myelin sheath morphology "malformation of the insulating envelope that surrounds nerve fibers or axons" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0004145 abnormal muscle electrophysiology "anomaly in the function of the musculature as it relates to electrical phenomena" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0004220 abnormal peripheral nervous system regeneration "changes in the ability or inability of healthy peripheral nervous system tissue to regenerate following injury or disease" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Scyl1mdf/Scyl1mdf
Genetic Background: involves: CFW * C57BL/6J * C57BR

 MP:0004243 abnormal motor nerve terminal sprouting "aberrant response of a motor neuron to form new neuritic processes (sprouts) that emerge from the nodes of Ranvier or terminal arborizations in response to nerve injury (such as denervation), application of nerve toxin, or muscle inactivity (usually due to disease)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0004509 abnormal pelvic girdle bone morphology "any structural anomaly of the bones of the pelvis by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0004565 small myocardial fiber "decreased size of the cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Scyl1tm1Spel/Scyl1tm1Spel,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0004819 decreased skeletal muscle mass "reduction in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Scyl1mdf/Scyl1mdf
Genetic Background: involves: CFW * C57BL/6J * C57BR

 MP:0005404 abnormal axon morphology "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0008572 abnormal Purkinje cell dendrite morphology "any strucutral anomaly of the Purkinje cell body projections with hundreds of parallel spiny branches reaching up into the molecular layer" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0008918 microgliosis "a proliferation or spread of microglia in the area of a degenerative lesion or damaged tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Scyl1tm1Spel/Scyl1tm1Spel,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0009403 increased variability of skeletal muscle fiber size "greater range or dispersion within a distribution of skeletal muscle fiber size within a muscle compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0009404 centrally nucleated skeletal muscle fibers "cell nuclei are located at a position in the center of the skeletal myofiber, instead of their normal location at the periphery of the fiber; may be indicative of centronuclear myopathy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Scyl1tm1Spel/Scyl1tm1Spel,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0009409 abnormal skeletal muscle fiber type ratio "deviation from the standard ratios of fiber types in a given skeletal muscle compared to control samples" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0009414 skeletal muscle fiber necrosis "pathological cell death in the skeletal muscle fibers, usually due to irreversible damage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
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Allelic Composition: Lamtor2tm1.1Lah/Lamtor2tm1.1Lah,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

Allelic Composition: Scyl1tm1.1Spel/Scyl1tm1.1Spel
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Scyl1tm1Spel/Scyl1tm1Spel,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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