ENSMUSG00000025240


Mus musculus

Features
Gene ID: ENSMUSG00000025240
  
Biological name :Sacm1l
  
Synonyms : Mus musculus SAC1 suppressor of actin mutations 1-like (yeast) (Sacm1l), transcript variant 1, mRNA. / Q9EP69 / Sacm1l
  
Possible biological names infered from orthology : Q9NTJ5 / SAC1 like phosphatidylinositide phosphatase
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F4
Gene start: 123529759
Gene end: 123592600
  
Corresponding Affymetrix probe sets: 10590597 (MoGene1.0st)   1416500_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026270
Ensembl peptide - ENSMUSP00000149326
NCBI entrez gene - 83493     See in Manteia.
MGI - MGI:1933169
RefSeq - XM_017313703
RefSeq - NM_001357485
RefSeq - NM_030692
RefSeq Peptide - NP_001344414
RefSeq Peptide - NP_109617
swissprot - Q9EP69
swissprot - A0A1L1SR59
Ensembl - ENSMUSG00000025240
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A4VCH0ENSDARG00000015290Danio rerio
 sacm1lbENSDARG00000059806Danio rerio
 SACM1LENSGALG00000040902Gallus gallus
 Q9NTJ5ENSG00000211456Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Inpp5f / Q8CDA1 / inositol polyphosphate-5-phosphatase F / Q9Y2H2*ENSMUSG0000004210533


Protein motifs (from Interpro)
Interpro ID Name
 IPR002013  SAC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0032281 AMPA glutamate receptor complex IDA
 molecular_functionGO:0004438 phosphatidylinositol-3-phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0034593 phosphatidylinositol bisphosphate phosphatase activity IEA
 molecular_functionGO:0042578 phosphoric ester hydrolase activity IEA
 molecular_functionGO:0043812 phosphatidylinositol-4-phosphate phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the ER membrane
Synthesis of PIPs at the Golgi membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Rock1tm1b(NCOM)Mfgc/Rock1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Rock1tm1b(NCOM)Mfgc/Tcp

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
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Allelic Composition: Rock1tm1b(NCOM)Mfgc/Rock1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Rock1tm1b(NCOM)Mfgc/Tcp

 MP:0002631 abnormal epididymis morphology "malformation of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Rock1tm1b(NCOM)Mfgc/Rock1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Rock1tm1b(NCOM)Mfgc/Tcp

 MP:0004931 enlarged epididymis "increase in the average size of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rock1tm1b(NCOM)Mfgc/Rock1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Rock1tm1b(NCOM)Mfgc/Tcp

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Rad9atm1.1(KOMP)Wtsi/Rad9atm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad9atm1.1(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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