ENSMUSG00000025409


Mus musculus

Features
Gene ID: ENSMUSG00000025409
  
Biological name :Mbd6
  
Synonyms : Mbd6 / Mus musculus methyl-CpG binding domain protein 6 (Mbd6), transcript variant 2, mRNA. / Q3TY92
  
Possible biological names infered from orthology : methyl-CpG binding domain protein 6 / Q96DN6
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D3
Gene start: 127281956
Gene end: 127289018
  
Corresponding Affymetrix probe sets: 10373143 (MoGene1.0st)   1418375_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122504
Ensembl peptide - ENSMUSP00000133835
Ensembl peptide - ENSMUSP00000134527
Ensembl peptide - ENSMUSP00000026476
Ensembl peptide - ENSMUSP00000112805
Ensembl peptide - ENSMUSP00000114590
Ensembl peptide - ENSMUSP00000115238
NCBI entrez gene - 110962     See in Manteia.
MGI - MGI:106378
RefSeq - XM_011243266
RefSeq - XM_006513075
RefSeq - XM_011243271
RefSeq - XM_011243270
RefSeq - XM_011243269
RefSeq - XM_011243268
RefSeq - NM_001347171
RefSeq - NM_033072
RefSeq - XM_011243272
RefSeq - XM_011243267
RefSeq Peptide - NP_149063
RefSeq Peptide - NP_001334100
swissprot - Q3TY92
swissprot - E9Q572
swissprot - D3YV97
swissprot - G3UZJ8
swissprot - G3UXV1
swissprot - F7CV40
swissprot - F6S711
Ensembl - ENSMUSG00000025409
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mbd6ENSDARG00000086980Danio rerio
 MBD6ENSG00000166987Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mbd5 / B1AYB6 / Methyl-CpG-binding domain protein 5 / Q9P267*ENSMUSG0000003679231


Protein motifs (from Interpro)
Interpro ID Name
 IPR001739  Methyl-CpG DNA binding
 IPR016177  DNA-binding domain superfamily
 IPR037385  Methyl-CpG-binding domain protein 5/6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0001650 fibrillar center ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0010369 chromocenter IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding ISS


Pathways (from Reactome)
Pathway description
UCH proteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Jam3tm1.1(KOMP)Vlcg/Jam3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Jam3tm1.1(KOMP)Vlcg/J

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Jam3tm1.1(KOMP)Vlcg/Jam3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Jam3tm1.1(KOMP)Vlcg/J

 MP:0013294 prenatal lethality prior to heart atrial septation "death prior to the completion of heart atrial septation (Mus: E14.5-15.5)" [MGI:smb]
Show

Allelic Composition: Jam3tm1.1(KOMP)Vlcg/Jam3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Jam3tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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